Poirot L - Search Results

1

Développement des CAR-T dans les tumeurs solides.

Alcazer V, Delenda C, Poirot L, Depil S. Alcazer V, et al. Among authors: poirot l. Bull Cancer. 2018 Dec;105 Suppl 2:S178-S187. doi: 10.1016/S0007-4551(19)30048-7. Bull Cancer. 2018. PMID: 30686356 Review. French.

2

Granulocyte-macrophage colony-stimulating factor inactivation in CAR T-cells prevents monocyte-dependent release of key cytokine release syndrome mediators.

Sachdeva M, Duchateau P, Depil S, Poirot L, Valton J. Sachdeva M, et al. Among authors: poirot l. J Biol Chem. 2019 Apr 5;294(14):5430-5437. doi: 10.1074/jbc.AC119.007558. Epub 2019 Feb 25. J Biol Chem. 2019. PMID: 30804212 Free PMC article.

3

Modulation of chimeric antigen receptor surface expression by a small molecule switch.

Juillerat A, Tkach D, Busser BW, Temburni S, Valton J, Duclert A, Poirot L, Depil S, Duchateau P. Juillerat A, et al. Among authors: poirot l. BMC Biotechnol. 2019 Jul 3;19(1):44. doi: 10.1186/s12896-019-0537-3. BMC Biotechnol. 2019. PMID: 31269942 Free PMC article.

4

Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality.

Sachdeva M, Busser BW, Temburni S, Jahangiri B, Gautron AS, Maréchal A, Juillerat A, Williams A, Depil S, Duchateau P, Poirot L, Valton J. Sachdeva M, et al. Among authors: poirot l. Nat Commun. 2019 Nov 13;10(1):5100. doi: 10.1038/s41467-019-13088-3. Nat Commun. 2019. PMID: 31723132 Free PMC article.

5

'Off-the-shelf' allogeneic CAR T cells: development and challenges.

Depil S, Duchateau P, Grupp SA, Mufti G, Poirot L. Depil S, et al. Among authors: poirot l. Nat Rev Drug Discov. 2020 Mar;19(3):185-199. doi: 10.1038/s41573-019-0051-2. Epub 2020 Jan 3. Nat Rev Drug Discov. 2020. PMID: 31900462 Review.

6

Author Correction: Repurposing endogenous immune pathways to tailor and control chimeric antigen receptor T cell functionality.

Sachdeva M, Busser BW, Temburni S, Jahangiri B, Gautron AS, Maréchal A, Juillerat A, Williams A, Depil S, Duchateau P, Poirot L, Valton J. Sachdeva M, et al. Among authors: poirot l. Nat Commun. 2020 May 7;11(1):2357. doi: 10.1038/s41467-020-16301-w. Nat Commun. 2020. PMID: 32382011 Free PMC article.

7

Stromal depletion by TALEN-edited universal hypoimmunogenic FAP-CAR T cells enables infiltration and anti-tumor cytotoxicity of tumor antigen-targeted CAR-T immunotherapy.

Das S, Valton J, Duchateau P, Poirot L. Das S, et al. Among authors: poirot l. Front Immunol. 2023 May 12;14:1172681. doi: 10.3389/fimmu.2023.1172681. eCollection 2023. Front Immunol. 2023. PMID: 37251405 Free PMC article.

8

A Multidrug-resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy.

Valton J, Guyot V, Marechal A, Filhol JM, Juillerat A, Duclert A, Duchateau P, Poirot L. Valton J, et al. Among authors: poirot l. Mol Ther. 2015 Sep;23(9):1507-18. doi: 10.1038/mt.2015.104. Epub 2015 Jun 10. Mol Ther. 2015. PMID: 26061646 Free PMC article.

9

TALEN-Mediated Inactivation of PD-1 in Tumor-Reactive Lymphocytes Promotes Intratumoral T-cell Persistence and Rejection of Established Tumors.

Menger L, Sledzinska A, Bergerhoff K, Vargas FA, Smith J, Poirot L, Pule M, Hererro J, Peggs KS, Quezada SA. Menger L, et al. Among authors: poirot l. Cancer Res. 2016 Apr 15;76(8):2087-93. doi: 10.1158/0008-5472.CAN-15-3352. Cancer Res. 2016. PMID: 27197251

10

Multiplex Genome-Edited T-cell Manufacturing Platform for "Off-the-Shelf" Adoptive T-cell Immunotherapies.

Poirot L, Philip B, Schiffer-Mannioui C, Le Clerre D, Chion-Sotinel I, Derniame S, Potrel P, Bas C, Lemaire L, Galetto R, Lebuhotel C, Eyquem J, Cheung GW, Duclert A, Gouble A, Arnould S, Peggs K, Pule M, Scharenberg AM, Smith J. Poirot L, et al. Cancer Res. 2015 Sep 15;75(18):3853-64. doi: 10.1158/0008-5472.CAN-14-3321. Epub 2015 Jul 16. Cancer Res. 2015. PMID: 26183927

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