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Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease.
Kam TI, Mao X, Park H, Chou SC, Karuppagounder SS, Umanah GE, Yun SP, Brahmachari S, Panicker N, Chen R, Andrabi SA, Qi C, Poirier GG, Pletnikova O, Troncoso JC, Bekris LM, Leverenz JB, Pantelyat A, Ko HS, Rosenthal LS, Dawson TM, Dawson VL. Kam TI, et al. Among authors: poirier gg. Science. 2018 Nov 2;362(6414):eaat8407. doi: 10.1126/science.aat8407. Science. 2018. PMID: 30385548 Free PMC article.
NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase.
Mandir AS, Poitras MF, Berliner AR, Herring WJ, Guastella DB, Feldman A, Poirier GG, Wang ZQ, Dawson TM, Dawson VL. Mandir AS, et al. Among authors: poirier gg. J Neurosci. 2000 Nov 1;20(21):8005-11. doi: 10.1523/JNEUROSCI.20-21-08005.2000. J Neurosci. 2000. PMID: 11050121 Free PMC article.
322 results