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Page 1
Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.
Amberg W, Lange UEW, Ochse M, Pohlki F, Behl B, Relo AL, Hornberger W, Hoft C, Mezler M, Sydor J, Wang Y, Zhao H, Brewer JT, Dietrich J, Li H, Akritopoulou-Zanze I, Lao Y, Hannick SM, Ku YY, Vasudevan A. Amberg W, et al. Among authors: pohlki f. J Med Chem. 2018 Sep 13;61(17):7503-7524. doi: 10.1021/acs.jmedchem.8b00300. Epub 2018 Aug 27. J Med Chem. 2018. PMID: 30080045
De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors.
Wang Y, Zhao H, Brewer JT, Li H, Lao Y, Amberg W, Behl B, Akritopoulou-Zanze I, Dietrich J, Lange UEW, Pohlki F, Hoft C, Hornberger W, Djuric SW, Sydor J, Mezler M, Relo AL, Vasudevan A. Wang Y, et al. Among authors: pohlki f. J Med Chem. 2018 Sep 13;61(17):7486-7502. doi: 10.1021/acs.jmedchem.8b00295. Epub 2018 Jul 17. J Med Chem. 2018. PMID: 29969029
Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
Petros AM, Korepanova A, Jakob CG, Qiu W, Panchal SC, Wang J, Dietrich JD, Brewer JT, Pohlki F, Kling A, Wilcox K, Lakics V, Bahnassawy L, Reinhardt P, Partha SK, Bodelle PM, Lake M, Charych EI, Stoll VS, Sun C, Mohler EG. Petros AM, et al. Among authors: pohlki f. J Med Chem. 2019 Apr 25;62(8):4120-4130. doi: 10.1021/acs.jmedchem.9b00178. Epub 2019 Apr 12. J Med Chem. 2019. PMID: 30933499
Total synthesis and stereochemical reassignment of (+)-neopeltolide.
Youngsaye W, Lowe JT, Pohlki F, Ralifo P, Panek JS. Youngsaye W, et al. Among authors: pohlki f. Angew Chem Int Ed Engl. 2007;46(48):9211-4. doi: 10.1002/anie.200704122. Angew Chem Int Ed Engl. 2007. PMID: 18022886 No abstract available.
The catalytic hydroamination of alkynes.
Pohlki F, Doye S. Pohlki F, et al. Chem Soc Rev. 2003 Mar;32(2):104-14. doi: 10.1039/b200386b. Chem Soc Rev. 2003. PMID: 12683107
The Mechanism of the.
Pohlki F, Doye S. Pohlki F, et al. Angew Chem Int Ed Engl. 2001 Jun 18;40(12):2305-2308. Angew Chem Int Ed Engl. 2001. PMID: 11433503 No abstract available.