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Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.
Elife. 2022 Dec 28;11:e81856. doi: 10.7554/eLife.81856.
Elife. 2022.
PMID: 36576240
Free PMC article.
MTCH2 is a mitochondrial outer membrane protein insertase.
Guna A, Stevens TA, Inglis AJ, Replogle JM, Esantsi TK, Muthukumar G, Shaffer KCL, Wang ML, Pogson AN, Jones JJ, Lomenick B, Chou TF, Weissman JS, Voorhees RM.
Guna A, et al. Among authors: pogson an.
Science. 2022 Oct 21;378(6617):317-322. doi: 10.1126/science.add1856. Epub 2022 Oct 20.
Science. 2022.
PMID: 36264797
Free PMC article.
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Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq.
Replogle JM, Saunders RA, Pogson AN, Hussmann JA, Lenail A, Guna A, Mascibroda L, Wagner EJ, Adelman K, Lithwick-Yanai G, Iremadze N, Oberstrass F, Lipson D, Bonnar JL, Jost M, Norman TM, Weissman JS.
Replogle JM, et al. Among authors: pogson an.
Cell. 2022 Jul 7;185(14):2559-2575.e28. doi: 10.1016/j.cell.2022.05.013. Epub 2022 Jun 9.
Cell. 2022.
PMID: 35688146
Free PMC article.
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Mapping transcriptomic vector fields of single cells.
Qiu X, Zhang Y, Martin-Rufino JD, Weng C, Hosseinzadeh S, Yang D, Pogson AN, Hein MY, Hoi Joseph Min K, Wang L, Grody EI, Shurtleff MJ, Yuan R, Xu S, Ma Y, Replogle JM, Lander ES, Darmanis S, Bahar I, Sankaran VG, Xing J, Weissman JS.
Qiu X, et al. Among authors: pogson an.
Cell. 2022 Feb 17;185(4):690-711.e45. doi: 10.1016/j.cell.2021.12.045. Epub 2022 Feb 1.
Cell. 2022.
PMID: 35108499
Free PMC article.
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Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing.
Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS.
Nuñez JK, et al. Among authors: pogson an.
Cell. 2021 Apr 29;184(9):2503-2519.e17. doi: 10.1016/j.cell.2021.03.025. Epub 2021 Apr 9.
Cell. 2021.
PMID: 33838111
Free PMC article.
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