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Corallopyronin A: antimicrobial discovery to preclinical development.
Krome AK, Becker T, Kehraus S, Schiefer A, Gütschow M, Chaverra-Muñoz L, Hüttel S, Jansen R, Stadler M, Ehrens A, Pogorevc D, Müller R, Hübner MP, Hesterkamp T, Pfarr K, Hoerauf A, Wagner KG, König GM. Krome AK, et al. Among authors: pogorevc d. Nat Prod Rep. 2022 Sep 21;39(9):1705-1720. doi: 10.1039/d2np00012a. Nat Prod Rep. 2022. PMID: 35730490 Review.
Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections.
Schiefer A, Hübner MP, Krome A, Lämmer C, Ehrens A, Aden T, Koschel M, Neufeld H, Chaverra-Muñoz L, Jansen R, Kehraus S, König GM, Pogorevc D, Müller R, Stadler M, Hüttel S, Hesterkamp T, Wagner K, Pfarr K, Hoerauf A. Schiefer A, et al. Among authors: pogorevc d. PLoS Negl Trop Dis. 2020 Dec 7;14(12):e0008930. doi: 10.1371/journal.pntd.0008930. eCollection 2020 Dec. PLoS Negl Trop Dis. 2020. PMID: 33284808 Free PMC article.
The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Wieland M, Holm M, Rundlet EJ, Morici M, Koller TO, Maviza TP, Pogorevc D, Osterman IA, Müller R, Blanchard SC, Wilson DN. Wieland M, et al. Among authors: pogorevc d. Proc Natl Acad Sci U S A. 2022 May 10;119(19):e2114214119. doi: 10.1073/pnas.2114214119. Epub 2022 May 2. Proc Natl Acad Sci U S A. 2022. PMID: 35500116 Free PMC article.
Biosynthesis and Heterologous Production of Argyrins.
Pogorevc D, Tang Y, Hoffmann M, Zipf G, Bernauer HS, Popoff A, Steinmetz H, Wenzel SC. Pogorevc D, et al. ACS Synth Biol. 2019 May 17;8(5):1121-1133. doi: 10.1021/acssynbio.9b00023. Epub 2019 Apr 24. ACS Synth Biol. 2019. PMID: 30995838