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Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms.
Prestipino A, Emhardt AJ, Aumann K, O'Sullivan D, Gorantla SP, Duquesne S, Melchinger W, Braun L, Vuckovic S, Boerries M, Busch H, Halbach S, Pennisi S, Poggio T, Apostolova P, Veratti P, Hettich M, Niedermann G, Bartholomä M, Shoumariyeh K, Jutzi JS, Wehrle J, Dierks C, Becker H, Schmitt-Graeff A, Follo M, Pfeifer D, Rohr J, Fuchs S, Ehl S, Hartl FA, Minguet S, Miething C, Heidel FH, Kröger N, Triviai I, Brummer T, Finke J, Illert AL, Ruggiero E, Bonini C, Duyster J, Pahl HL, Lane SW, Hill GR, Blazar BR, von Bubnoff N, Pearce EL, Zeiser R. Prestipino A, et al. Among authors: poggio t. Sci Transl Med. 2018 Feb 21;10(429):eaam7729. doi: 10.1126/scitranslmed.aam7729. Sci Transl Med. 2018. PMID: 29467301 Free PMC article.
NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia.
Rudorf A, Müller TA, Klingeberg C, Kreutmair S, Poggio T, Gorantla SP, Rückert T, Schmitt-Graeff A, Gengenbacher A, Paschka P, Baldus C, Zeiser R, Vassiliou GS, Bradley A, Duyster J, Illert AL. Rudorf A, et al. Among authors: poggio t. Blood. 2019 Jul 25;134(4):383-388. doi: 10.1182/blood.2018883140. Epub 2019 Jun 11. Blood. 2019. PMID: 31186273 Free PMC article.
A novel conditional NPM-ALK-driven model of CD30+ T-cell lymphoma mediated by a translational stop cassette.
Shoumariyeh K, Schneider N, Poggio T, Veratti P, Ehrenfeld S, Redhaber DM, Khan R, Pfeifer D, Klingeberg C, Kreutmair S, Rudelius M, Quintanilla-Martinez L, Fend F, Illert AL, Duyster J, Miething C. Shoumariyeh K, et al. Among authors: poggio t. Oncogene. 2020 Feb;39(9):1904-1913. doi: 10.1038/s41388-019-1058-1. Epub 2019 Nov 21. Oncogene. 2020. PMID: 31754210
Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model.
Kreutmair S, Klingeberg C, Poggio T, Andrieux G, Keller A, Miething C, Follo M, Pfeifer D, Shoumariyeh K, Lengerke C, Gonzalez-Menendez I, Fend F, Zeiser R, Turner SD, Quintanilla-Martinez L, Boerries M, Duyster J, Illert AL. Kreutmair S, et al. Among authors: poggio t. Leukemia. 2020 Dec;34(12):3242-3255. doi: 10.1038/s41375-020-0789-x. Epub 2020 Mar 17. Leukemia. 2020. PMID: 32203142 Free PMC article.
Loss of the Fanconi anemia-associated protein NIPA causes bone marrow failure.
Kreutmair S, Erlacher M, Andrieux G, Istvanffy R, Mueller-Rudorf A, Zwick M, Rückert T, Pantic M, Poggio T, Shoumariyeh K, Mueller TA, Kawaguchi H, Follo M, Klingeberg C, Wlodarski M, Baumann I, Pfeifer D, Kulinski M, Rudelius M, Lemeer S, Kuster B, Dierks C, Peschel C, Cabezas-Wallscheid N, Duque-Afonso J, Zeiser R, Cleary ML, Schindler D, Schmitt-Graeff A, Boerries M, Niemeyer CM, Oostendorp RA, Duyster J, Illert AL. Kreutmair S, et al. Among authors: poggio t. J Clin Invest. 2020 Jun 1;130(6):2827-2844. doi: 10.1172/JCI126215. J Clin Invest. 2020. PMID: 32338640 Free PMC article.
Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo.
Spohr C, Poggio T, Andrieux G, Schönberger K, Cabezas-Wallscheid N, Boerries M, Halbach S, Illert AL, Brummer T. Spohr C, et al. Among authors: poggio t. Leukemia. 2022 Apr;36(4):970-982. doi: 10.1038/s41375-021-01490-0. Epub 2021 Dec 13. Leukemia. 2022. PMID: 34903841 Free PMC article.
Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL.
Gentile G, Poggio T, Catalano A, Voutilainen M, Lahnalampi M, Andrade-Martinez M, Ma T, Sankowski R, Goncharenko L, Tholen S, Han K, Morgens DW, Prinz M, Lübbert M, Engel S, Hartmann TN, Cario G, Schrappe M, Lenk L, Stanulla M, Duyster J, Bronsert P, Bassik M, Cleary ML, Schilling O, Heinäniemi M, Duque-Afonso J. Gentile G, et al. Among authors: poggio t. Blood Adv. 2024 Apr 10:bloodadvances.2023011582. doi: 10.1182/bloodadvances.2023011582. Online ahead of print. Blood Adv. 2024. PMID: 38598725
136 results