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Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri-Specific CYP51 Inhibitors.
Sharma V, Madia VN, Tudino V, Nguyen JV, Debnath A, Messore A, Ialongo D, Patacchini E, Palenca I, Basili Franzin S, Seguella L, Esposito G, Petrucci R, Di Matteo P, Bortolami M, Saccoliti F, Di Santo R, Scipione L, Costi R, Podust LM. Sharma V, et al. Among authors: podust lm. J Med Chem. 2023 Dec 28;66(24):17059-17073. doi: 10.1021/acs.jmedchem.3c01898. Epub 2023 Dec 12. J Med Chem. 2023. PMID: 38085955 Free PMC article.
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.
Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Pepe G, Cirilli R, Faggi C, Di Marco A, Battista MR, Summa V, Costi R, Di Santo R. Saccoliti F, et al. Among authors: podust lm. J Med Chem. 2019 Feb 14;62(3):1330-1347. doi: 10.1021/acs.jmedchem.8b01464. Epub 2019 Jan 23. J Med Chem. 2019. PMID: 30615444
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents.
Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Costi R, Di Santo R. Saccoliti F, et al. Among authors: podust lm. Eur J Med Chem. 2018 Aug 5;156:53-60. doi: 10.1016/j.ejmech.2018.06.063. Epub 2018 Jun 28. Eur J Med Chem. 2018. PMID: 30006174
HMG-CoA Reductase Inhibitors as Drug Leads against Naegleria fowleri.
Hahn HJ, Abagyan R, Podust LM, Roy S, Ali IKM, Debnath A. Hahn HJ, et al. Among authors: podust lm. ACS Chem Neurosci. 2020 Oct 7;11(19):3089-3096. doi: 10.1021/acschemneuro.0c00428. Epub 2020 Sep 19. ACS Chem Neurosci. 2020. PMID: 32881478 Free PMC article.
91 results