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SERPINB9 is commonly amplified and high expression in cancer cells correlates with poor immune checkpoint blockade response.
Ibáñez-Molero S, van Vliet A, Pozniak J, Hummelink K, Terry AM, Monkhorst K, Sanders J, Hofland I, Landeloos E, Van Herck Y, Bechter O, Kuilman T, Zhong W, Marine JC, Wessels L, Peeper DS. Ibáñez-Molero S, et al. Among authors: pozniak j. Oncoimmunology. 2022 Nov 29;11(1):2139074. doi: 10.1080/2162402X.2022.2139074. eCollection 2022. Oncoimmunology. 2022. PMID: 36465485 Free PMC article.
The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity.
Ho P, Melms JC, Rogava M, Frangieh CJ, Poźniak J, Shah SB, Walsh Z, Kyrysyuk O, Amin AD, Caprio L, Fullerton BT, Soni RK, Ager CR, Biermann J, Wang Y, Khosravi-Maharlooei M, Zanetti G, Mu M, Fatima H, Moore EK, Vasan N, Bakhoum SF, Reiner SL, Bernatchez C, Sykes M, Mace EM, Wucherpfennig KW, Schadendorf D, Bechter O, Shah P, Schwartz GK, Marine JC, Izar B. Ho P, et al. Among authors: pozniak j. Cancer Cell. 2023 Jul 10;41(7):1207-1221.e12. doi: 10.1016/j.ccell.2023.05.014. Epub 2023 Jun 15. Cancer Cell. 2023. PMID: 37327789
Transcriptomic Analysis Reveals Prognostic Molecular Signatures of Stage I Melanoma.
Thakur R, Laye JP, Lauss M, Diaz JMS, O'Shea SJ, Poźniak J, Filia A, Harland M, Gascoyne J, Randerson-Moor JA, Chan M, Mell T, Jönsson G, Bishop DT, Newton-Bishop J, Barrett JH, Nsengimana J. Thakur R, et al. Among authors: pozniak j. Clin Cancer Res. 2019 Dec 15;25(24):7424-7435. doi: 10.1158/1078-0432.CCR-18-3659. Epub 2019 Sep 12. Clin Cancer Res. 2019. PMID: 31515461 Free article.
Genetic and Environmental Determinants of Immune Response to Cutaneous Melanoma.
Poźniak J, Nsengimana J, Laye JP, O'Shea SJ, Diaz JMS, Droop AP, Filia A, Harland M, Davies JR, Mell T, Randerson-Moor JA, Muralidhar S, Hogan SA, Freiberger SN, Levesque MP, Cook GP, Bishop DT, Newton-Bishop J. Poźniak J, et al. Cancer Res. 2019 May 15;79(10):2684-2696. doi: 10.1158/0008-5472.CAN-18-2864. Epub 2019 Feb 17. Cancer Res. 2019. PMID: 30773503 Free PMC article.
β-Catenin-mediated immune evasion pathway frequently operates in primary cutaneous melanomas.
Nsengimana J, Laye J, Filia A, O'Shea S, Muralidhar S, Poźniak J, Droop A, Chan M, Walker C, Parkinson L, Gascoyne J, Mell T, Polso M, Jewell R, Randerson-Moor J, Cook GP, Bishop DT, Newton-Bishop J. Nsengimana J, et al. Among authors: pozniak j. J Clin Invest. 2018 May 1;128(5):2048-2063. doi: 10.1172/JCI95351. Epub 2018 Apr 16. J Clin Invest. 2018. PMID: 29664013 Free PMC article.
High-Resolution Copy Number Patterns From Clinically Relevant FFPE Material.
Filia A, Droop A, Harland M, Thygesen H, Randerson-Moor J, Snowden H, Taylor C, Diaz JMS, Pozniak J, Nsengimana J, Laye J, Newton-Bishop JA, Bishop DT. Filia A, et al. Among authors: pozniak j. Sci Rep. 2019 Jun 20;9(1):8908. doi: 10.1038/s41598-019-45210-2. Sci Rep. 2019. PMID: 31222134 Free PMC article.
MX 2 is a novel regulator of cell cycle in melanoma cells.
Juraleviciute M, Pozniak J, Nsengimana J, Harland M, Randerson-Moor J, Wernhoff P, Bassarova A, Øy GF, Trøen G, Flørenes VA, Bishop DT, Herlyn M, Newton-Bishop J, Slipicevic A. Juraleviciute M, et al. Among authors: pozniak j. Pigment Cell Melanoma Res. 2020 May;33(3):446-457. doi: 10.1111/pcmr.12837. Epub 2019 Nov 13. Pigment Cell Melanoma Res. 2020. PMID: 31660681 Free PMC article.
Vitamin D-VDR Signaling Inhibits Wnt/β-Catenin-Mediated Melanoma Progression and Promotes Antitumor Immunity.
Muralidhar S, Filia A, Nsengimana J, Poźniak J, O'Shea SJ, Diaz JM, Harland M, Randerson-Moor JA, Reichrath J, Laye JP, van der Weyden L, Adams DJ, Bishop DT, Newton-Bishop J. Muralidhar S, et al. Among authors: pozniak j. Cancer Res. 2019 Dec 1;79(23):5986-5998. doi: 10.1158/0008-5472.CAN-18-3927. Epub 2019 Nov 5. Cancer Res. 2019. PMID: 31690667 Free article.
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