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Impaired dopamine metabolism in Parkinson's disease pathogenesis.
Masato A, Plotegher N, Boassa D, Bubacco L. Masato A, et al. Among authors: plotegher n. Mol Neurodegener. 2019 Aug 20;14(1):35. doi: 10.1186/s13024-019-0332-6. Mol Neurodegener. 2019. PMID: 31488222 Free PMC article. Review.
Alpha-synuclein pore forming activity upon membrane association.
Tosatto L, Andrighetti AO, Plotegher N, Antonini V, Tessari I, Ricci L, Bubacco L, Dalla Serra M. Tosatto L, et al. Among authors: plotegher n. Biochim Biophys Acta. 2012 Nov;1818(11):2876-83. doi: 10.1016/j.bbamem.2012.07.007. Epub 2012 Jul 20. Biochim Biophys Acta. 2012. PMID: 22820150 Free article.
The chaperone-like protein 14-3-3η interacts with human α-synuclein aggregation intermediates rerouting the amyloidogenic pathway and reducing α-synuclein cellular toxicity.
Plotegher N, Kumar D, Tessari I, Brucale M, Munari F, Tosatto L, Belluzzi E, Greggio E, Bisaglia M, Capaldi S, Aioanei D, Mammi S, Monaco HL, Samo B, Bubacco L. Plotegher N, et al. Hum Mol Genet. 2014 Nov 1;23(21):5615-29. doi: 10.1093/hmg/ddu275. Epub 2014 Jun 3. Hum Mol Genet. 2014. PMID: 24895406
LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate.
Belluzzi E, Gonnelli A, Cirnaru MD, Marte A, Plotegher N, Russo I, Civiero L, Cogo S, Carrion MP, Franchin C, Arrigoni G, Beltramini M, Bubacco L, Onofri F, Piccoli G, Greggio E. Belluzzi E, et al. Among authors: plotegher n. Mol Neurodegener. 2016 Jan 13;11:1. doi: 10.1186/s13024-015-0066-z. Mol Neurodegener. 2016. PMID: 26758690 Free PMC article.
39 results