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Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
Nielsen HB, Almeida M, Juncker AS, Rasmussen S, Li J, Sunagawa S, Plichta DR, Gautier L, Pedersen AG, Le Chatelier E, Pelletier E, Bonde I, Nielsen T, Manichanh C, Arumugam M, Batto JM, Quintanilha Dos Santos MB, Blom N, Borruel N, Burgdorf KS, Boumezbeur F, Casellas F, Doré J, Dworzynski P, Guarner F, Hansen T, Hildebrand F, Kaas RS, Kennedy S, Kristiansen K, Kultima JR, Léonard P, Levenez F, Lund O, Moumen B, Le Paslier D, Pons N, Pedersen O, Prifti E, Qin J, Raes J, Sørensen S, Tap J, Tims S, Ussery DW, Yamada T; MetaHIT Consortium; Renault P, Sicheritz-Ponten T, Bork P, Wang J, Brunak S, Ehrlich SD; MetaHIT Consortium. Nielsen HB, et al. Among authors: plichta dr. Nat Biotechnol. 2014 Aug;32(8):822-8. doi: 10.1038/nbt.2939. Epub 2014 Jul 6. Nat Biotechnol. 2014. PMID: 24997787
A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning.
Vatanen T, Ang QY, Siegwald L, Sarker SA, Le Roy CI, Duboux S, Delannoy-Bruno O, Ngom-Bru C, Boulangé CL, Stražar M, Avila-Pacheco J, Deik A, Pierce K, Bullock K, Dennis C, Sultana S, Sayed S, Rahman M, Ahmed T, Modesto M, Mattarelli P, Clish CB, Vlamakis H, Plichta DR, Sakwinska O, Xavier RJ. Vatanen T, et al. Among authors: plichta dr. Cell. 2022 Nov 10;185(23):4280-4297.e12. doi: 10.1016/j.cell.2022.10.011. Epub 2022 Nov 1. Cell. 2022. PMID: 36323316 Free article.
Human gut microbes impact host serum metabolome and insulin sensitivity.
Pedersen HK, Gudmundsdottir V, Nielsen HB, Hyotylainen T, Nielsen T, Jensen BA, Forslund K, Hildebrand F, Prifti E, Falony G, Le Chatelier E, Levenez F, Doré J, Mattila I, Plichta DR, Pöhö P, Hellgren LI, Arumugam M, Sunagawa S, Vieira-Silva S, Jørgensen T, Holm JB, Trošt K; MetaHIT Consortium; Kristiansen K, Brix S, Raes J, Wang J, Hansen T, Bork P, Brunak S, Oresic M, Ehrlich SD, Pedersen O. Pedersen HK, et al. Among authors: plichta dr. Nature. 2016 Jul 21;535(7612):376-81. doi: 10.1038/nature18646. Epub 2016 Jul 13. Nature. 2016. PMID: 27409811
Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut.
Roager HM, Hansen LB, Bahl MI, Frandsen HL, Carvalho V, Gøbel RJ, Dalgaard MD, Plichta DR, Sparholt MH, Vestergaard H, Hansen T, Sicheritz-Pontén T, Nielsen HB, Pedersen O, Lauritzen L, Kristensen M, Gupta R, Licht TR. Roager HM, et al. Among authors: plichta dr. Nat Microbiol. 2016 Jun 27;1(9):16093. doi: 10.1038/nmicrobiol.2016.93. Nat Microbiol. 2016. PMID: 27562254
Transcriptional interactions suggest niche segregation among microorganisms in the human gut.
Plichta DR, Juncker AS, Bertalan M, Rettedal E, Gautier L, Varela E, Manichanh C, Fouqueray C, Levenez F, Nielsen T, Doré J, Machado AM, de Evgrafov MC, Hansen T, Jørgensen T, Bork P, Guarner F, Pedersen O; Metagenomics of the Human Intestinal Tract (MetaHIT) Consortium; Sommer MO, Ehrlich SD, Sicheritz-Pontén T, Brunak S, Nielsen HB. Plichta DR, et al. Nat Microbiol. 2016 Aug 26;1(11):16152. doi: 10.1038/nmicrobiol.2016.152. Nat Microbiol. 2016. PMID: 27564131
Genome binning of viral entities from bulk metagenomics data.
Johansen J, Plichta DR, Nissen JN, Jespersen ML, Shah SA, Deng L, Stokholm J, Bisgaard H, Nielsen DS, Sørensen SJ, Rasmussen S. Johansen J, et al. Among authors: plichta dr. Nat Commun. 2022 Feb 18;13(1):965. doi: 10.1038/s41467-022-28581-5. Nat Commun. 2022. PMID: 35181661 Free PMC article.
Genomic variation and strain-specific functional adaptation in the human gut microbiome during early life.
Vatanen T, Plichta DR, Somani J, Münch PC, Arthur TD, Hall AB, Rudolf S, Oakeley EJ, Ke X, Young RA, Haiser HJ, Kolde R, Yassour M, Luopajärvi K, Siljander H, Virtanen SM, Ilonen J, Uibo R, Tillmann V, Mokurov S, Dorshakova N, Porter JA, McHardy AC, Lähdesmäki H, Vlamakis H, Huttenhower C, Knip M, Xavier RJ. Vatanen T, et al. Among authors: plichta dr. Nat Microbiol. 2019 Mar;4(3):470-479. doi: 10.1038/s41564-018-0321-5. Epub 2018 Dec 17. Nat Microbiol. 2019. PMID: 30559407 Free PMC article.
Discovery of bioactive microbial gene products in inflammatory bowel disease.
Zhang Y, Bhosle A, Bae S, McIver LJ, Pishchany G, Accorsi EK, Thompson KN, Arze C, Wang Y, Subramanian A, Kearney SM, Pawluk A, Plichta DR, Rahnavard A, Shafquat A, Xavier RJ, Vlamakis H, Garrett WS, Krueger A, Huttenhower C, Franzosa EA. Zhang Y, et al. Among authors: plichta dr. Nature. 2022 Jun;606(7915):754-760. doi: 10.1038/s41586-022-04648-7. Epub 2022 May 25. Nature. 2022. PMID: 35614211 Free PMC article.
36 results