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Independent structural domains in paramyxovirus polymerase protein.
Dochow M, Krumm SA, Crowe JE Jr, Moore ML, Plemper RK. Dochow M, et al. Among authors: plemper rk. J Biol Chem. 2012 Feb 24;287(9):6878-91. doi: 10.1074/jbc.M111.325258. Epub 2012 Jan 3. J Biol Chem. 2012. PMID: 22215662 Free PMC article.
An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model.
Krumm SA, Yan D, Hovingh ES, Evers TJ, Enkirch T, Reddy GP, Sun A, Saindane MT, Arrendale RF, Painter G, Liotta DC, Natchus MG, von Messling V, Plemper RK. Krumm SA, et al. Among authors: plemper rk. Sci Transl Med. 2014 Apr 16;6(232):232ra52. doi: 10.1126/scitranslmed.3008517. Sci Transl Med. 2014. PMID: 24739760 Free PMC article.
140 results