Platzek J - Search Results

1

Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839.

Bothe U, Günther J, Nubbemeyer R, Siebeneicher H, Ring S, Bömer U, Peters M, Rausch A, Denner K, Himmel H, Sutter A, Terebesi I, Lange M, Wengner AM, Guimond N, Thaler T, Platzek J, Eberspächer U, Schäfer M, Steuber H, Zollner TM, Steinmeyer A, Schmidt N. Bothe U, et al. Among authors: platzek j. J Med Chem. 2024 Jan 25;67(2):1225-1242. doi: 10.1021/acs.jmedchem.3c01714. Epub 2024 Jan 16. J Med Chem. 2024. PMID: 38228402 Free PMC article.

2

Discovery of BAY 94-8862: a nonsteroidal antagonist of the mineralocorticoid receptor for the treatment of cardiorenal diseases.

Bärfacker L, Kuhl A, Hillisch A, Grosser R, Figueroa-Pérez S, Heckroth H, Nitsche A, Ergüden JK, Gielen-Haertwig H, Schlemmer KH, Mittendorf J, Paulsen H, Platzek J, Kolkhof P. Bärfacker L, et al. Among authors: platzek j. ChemMedChem. 2012 Aug;7(8):1385-403. doi: 10.1002/cmdc.201200081. Epub 2012 Jul 12. ChemMedChem. 2012. PMID: 22791416

3

Equilibrium, 1H and 13C NMR spectroscopy, and X-ray diffraction studies on the complexes Bi(DOTA)- and Bi(DO3A-Bu).

Csajbók E, Baranyai Z, Bányai I, Brücher E, Király R, Müller-Fahrnow A, Platzek J, Radüchel B, Schäfer M. Csajbók E, et al. Among authors: platzek j. Inorg Chem. 2003 Apr 7;42(7):2342-9. doi: 10.1021/ic0261272. Inorg Chem. 2003. PMID: 12665368

4

Synthesis and Physicochemical Characterization of a New Gadolinium Chelate: The Liver-Specific Magnetic Resonance Imaging Contrast Agent Gd-EOB-DTPA.

Schmitt-Willich H, Brehm M, Ewers CL, Michl G, Müller-Fahrnow A, Petrov O, Platzek J, Radüchel B, Sülzle D. Schmitt-Willich H, et al. Among authors: platzek j. Inorg Chem. 1999 Mar 22;38(6):1134-1144. doi: 10.1021/ic981072i. Inorg Chem. 1999. PMID: 11670895

5

Synthesis and Structure of a New Macrocyclic Polyhydroxylated Gadolinium Chelate Used as a Contrast Agent for Magnetic Resonance Imaging.

Platzek J, Blaszkiewicz P, Gries H, Luger P, Michl G, Müller-Fahrnow A, Radüchel B, Sülzle D. Platzek J, et al. Inorg Chem. 1997 Dec 17;36(26):6086-6093. doi: 10.1021/ic970123t. Inorg Chem. 1997. PMID: 11670244

6

Enantioselective Total Synthesis of (-)-Finerenone Using Asymmetric Transfer Hydrogenation.

Lerchen A, Gandhamsetty N, Farrar EHE, Winter N, Platzek J, Grayson MN, Aggarwal VK. Lerchen A, et al. Among authors: platzek j. Angew Chem Int Ed Engl. 2020 Dec 14;59(51):23107-23111. doi: 10.1002/anie.202011256. Epub 2020 Nov 23. Angew Chem Int Ed Engl. 2020. PMID: 32890415 Free PMC article.

7

Biocatalysis at Work: Applications in the Development of Sagopilone.

Gottfried K, Klar U, Platzek J, Zorn L. Gottfried K, et al. Among authors: platzek j. ChemMedChem. 2015 Jul;10(7):1240-8. doi: 10.1002/cmdc.201500138. Epub 2015 May 28. ChemMedChem. 2015. PMID: 26018455

8

Biotransformation of Finerenone, a Novel Nonsteroidal Mineralocorticoid Receptor Antagonist, in Dogs, Rats, and Humans, In Vivo and In Vitro.

Gerisch M, Heinig R, Engelen A, Lang D, Kolkhof P, Radtke M, Platzek J, Lovis K, Rohde G, Schwarz T. Gerisch M, et al. Among authors: platzek j. Drug Metab Dispos. 2018 Nov;46(11):1546-1555. doi: 10.1124/dmd.118.083337. Epub 2018 Aug 31. Drug Metab Dispos. 2018. PMID: 30171161 Clinical Trial.

9

Comparative studies on the efficacy of MRI contrast agents in MRA.

Weinmann HJ, Bauer H, Ebert W, Frenzel T, Radüchel B, Platzek J, Schmitt-Willich H. Weinmann HJ, et al. Among authors: platzek j. Acad Radiol. 2002 May;9 Suppl 1:S135-6. doi: 10.1016/s1076-6332(03)80419-1. Acad Radiol. 2002. PMID: 12019849 No abstract available.

10

Noninvasive temperature measurement in vivo using a temperature-sensitive lanthanide complex and 1H magnetic resonance spectroscopy.

Frenzel T, Roth K, Kossler S, Radüchel B, Bauer H, Platzek J, Weinmann HJ. Frenzel T, et al. Among authors: platzek j. Magn Reson Med. 1996 Mar;35(3):364-9. doi: 10.1002/mrm.1910350314. Magn Reson Med. 1996. PMID: 8699948

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