Platt RJ - Search Results

1

Integrated compact regulators of protein activity enable control of signaling pathways and genome-editing in vivo.

Franko N, da Silva Santinha AJ, Xue S, Zhao H, Charpin-El Hamri G, Platt RJ, Teixeira AP, Fussenegger M. Franko N, et al. Among authors: platt rj. Cell Discov. 2024 Jan 23;10(1):9. doi: 10.1038/s41421-023-00632-1. Cell Discov. 2024. PMID: 38263404 Free PMC article.

2

Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction.

Shi X, Lu C, Corman A, Nikish A, Zhou Y, Platt RJ, Iossifov I, Zhang F, Pan JQ, Sanjana NE. Shi X, et al. Among authors: platt rj. Am J Hum Genet. 2023 Oct 5;110(10):1750-1768. doi: 10.1016/j.ajhg.2023.09.004. Am J Hum Genet. 2023. PMID: 37802044 Free PMC article.

3

Fast, multiplexable and efficient somatic gene deletions in adult mouse skeletal muscle fibers using AAV-CRISPR/Cas9.

Thürkauf M, Lin S, Oliveri F, Grimm D, Platt RJ, Rüegg MA. Thürkauf M, et al. Among authors: platt rj. Nat Commun. 2023 Sep 30;14(1):6116. doi: 10.1038/s41467-023-41769-7. Nat Commun. 2023. PMID: 37777530 Free PMC article.

4

Transcriptional linkage analysis with in vivo AAV-Perturb-seq.

Santinha AJ, Klingler E, Kuhn M, Farouni R, Lagler S, Kalamakis G, Lischetti U, Jabaudon D, Platt RJ. Santinha AJ, et al. Among authors: platt rj. Nature. 2023 Oct;622(7982):367-375. doi: 10.1038/s41586-023-06570-y. Epub 2023 Sep 20. Nature. 2023. PMID: 37730998 Free PMC article.

5

CRISPR for neuroscientists.

Kalamakis G, Platt RJ. Kalamakis G, et al. Among authors: platt rj. Neuron. 2023 Aug 2;111(15):2282-2311. doi: 10.1016/j.neuron.2023.04.021. Epub 2023 May 17. Neuron. 2023. PMID: 37201524 Review.

6

Microbial medics diagnose and treat gut inflammation.

Tanna T, Platt RJ. Tanna T, et al. Among authors: platt rj. Cell Host Microbe. 2023 Feb 8;31(2):164-166. doi: 10.1016/j.chom.2023.01.012. Cell Host Microbe. 2023. PMID: 36758514 Free article.

7

Noninvasive assessment of gut function using transcriptional recording sentinel cells.

Schmidt F, Zimmermann J, Tanna T, Farouni R, Conway T, Macpherson AJ, Platt RJ. Schmidt F, et al. Among authors: platt rj. Science. 2022 May 13;376(6594):eabm6038. doi: 10.1126/science.abm6038. Epub 2022 May 13. Science. 2022. PMID: 35549411

8

miR-137 and miR-122, two outer subventricular zone non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation.

Tomasello U, Klingler E, Niquille M, Mule N, Santinha AJ, de Vevey L, Prados J, Platt RJ, Borrell V, Jabaudon D, Dayer A. Tomasello U, et al. Among authors: platt rj. Cell Rep. 2022 Feb 15;38(7):110381. doi: 10.1016/j.celrep.2022.110381. Cell Rep. 2022. PMID: 35172154 Free PMC article.

9

An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression.

Scheidmann MC, Castro-Giner F, Strittmatter K, Krol I, Paasinen-Sohns A, Scherrer R, Donato C, Gkountela S, Szczerba BM, Diamantopoulou Z, Muenst S, Vlajnic T, Kunz L, Vetter M, Rochlitz C, Taylor V, Giachino C, Schroeder T, Platt RJ, Aceto N. Scheidmann MC, et al. Among authors: platt rj. Cancer Res. 2022 Feb 15;82(4):681-694. doi: 10.1158/0008-5472.CAN-21-3908. Cancer Res. 2022. PMID: 34916221 Free PMC article.

10

Multiplexed Genome Engineering with Cas12a.

Weisbach NR, Meijs A, Platt RJ. Weisbach NR, et al. Among authors: platt rj. Methods Mol Biol. 2021;2312:171-192. doi: 10.1007/978-1-0716-1441-9_11. Methods Mol Biol. 2021. PMID: 34228291

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