Plater A - Search Results

1

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention.

Summers RL, Pasaje CFA, Pisco JP, Striepen J, Luth MR, Kumpornsin K, Carpenter EF, Munro JT, Lin D, Plater A, Punekar AS, Shepherd AM, Shepherd SM, Vanaerschot M, Murithi JM, Rubiano K, Akidil A, Ottilie S, Mittal N, Dilmore AH, Won M, Mandt REK, McGowen K, Owen E, Walpole C, Llinás M, Lee MCS, Winzeler EA, Fidock DA, Gilbert IH, Wirth DF, Niles JC, Baragaña B, Lukens AK. Summers RL, et al. Among authors: plater a. Cell Chem Biol. 2022 Feb 17;29(2):191-201.e8. doi: 10.1016/j.chembiol.2021.07.010. Epub 2021 Aug 3. Cell Chem Biol. 2022. PMID: 34348113 Free PMC article.

2

Prioritization of Molecular Targets for Antimalarial Drug Discovery.

Forte B, Ottilie S, Plater A, Campo B, Dechering KJ, Gamo FJ, Goldberg DE, Istvan ES, Lee M, Lukens AK, McNamara CW, Niles JC, Okombo J, Pasaje CFA, Siegel MG, Wirth D, Wyllie S, Fidock DA, Baragaña B, Winzeler EA, Gilbert IH. Forte B, et al. Among authors: plater a. ACS Infect Dis. 2021 Oct 8;7(10):2764-2776. doi: 10.1021/acsinfecdis.1c00322. Epub 2021 Sep 15. ACS Infect Dis. 2021. PMID: 34523908 Free PMC article.

3

REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors.

Andrews MJ, Kontopidis G, McInnes C, Plater A, Innes L, Cowan A, Jewsbury P, Fischer PM. Andrews MJ, et al. Among authors: plater a. Chembiochem. 2006 Dec;7(12):1909-15. doi: 10.1002/cbic.200600189. Chembiochem. 2006. PMID: 17051658

4

Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange.

Kontopidis G, Andrews MJ, McInnes C, Cowan A, Powers H, Innes L, Plater A, Griffiths G, Paterson D, Zheleva DI, Lane DP, Green S, Walkinshaw MD, Fischer PM. Kontopidis G, et al. Among authors: plater a. Structure. 2003 Dec;11(12):1537-46. doi: 10.1016/j.str.2003.11.006. Structure. 2003. PMID: 14656438 Free article.

5

Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes.

Andrews MJ, McInnes C, Kontopidis G, Innes L, Cowan A, Plater A, Fischer PM. Andrews MJ, et al. Among authors: plater a. Org Biomol Chem. 2004 Oct 7;2(19):2735-41. doi: 10.1039/B409157D. Epub 2004 Sep 9. Org Biomol Chem. 2004. PMID: 15455144

6

Truncation and optimisation of peptide inhibitors of cyclin-dependent kinase 2-cyclin a through structure-guided design.

Kontopidis G, Andrews MJ, McInnes C, Plater A, Innes L, Renachowski S, Cowan A, Fischer PM. Kontopidis G, et al. Among authors: plater a. ChemMedChem. 2009 Jul;4(7):1120-8. doi: 10.1002/cmdc.200900093. ChemMedChem. 2009. PMID: 19472269

7

Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors.

Wang S, Midgley CA, Scaërou F, Grabarek JB, Griffiths G, Jackson W, Kontopidis G, McClue SJ, McInnes C, Meades C, Mezna M, Plater A, Stuart I, Thomas MP, Wood G, Clarke RG, Blake DG, Zheleva DI, Lane DP, Jackson RC, Glover DM, Fischer PM. Wang S, et al. Among authors: plater a. J Med Chem. 2010 Jun 10;53(11):4367-78. doi: 10.1021/jm901913s. J Med Chem. 2010. PMID: 20462263

8

A functional role for a flexible loop containing Glu182 in the class II fructose-1,6-bisphosphate aldolase from Escherichia coli.

Zgiby S, Plater AR, Bates MA, Thomson GJ, Berry A. Zgiby S, et al. Among authors: plater ar. J Mol Biol. 2002 Jan 11;315(2):131-40. doi: 10.1006/jmbi.2001.5237. J Mol Biol. 2002. PMID: 11779234

9

Conserved residues in the mechanism of the E. coli Class II FBP-aldolase.

Plater AR, Zgiby SM, Thomson GJ, Qamar S, Wharton CW, Berry A. Plater AR, et al. J Mol Biol. 1999 Jan 15;285(2):843-55. doi: 10.1006/jmbi.1998.2376. J Mol Biol. 1999. PMID: 9878448

10

The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold.

Cooper SJ, Leonard GA, McSweeney SM, Thompson AW, Naismith JH, Qamar S, Plater A, Berry A, Hunter WN. Cooper SJ, et al. Among authors: plater a. Structure. 1996 Nov 15;4(11):1303-15. doi: 10.1016/s0969-2126(96)00138-4. Structure. 1996. PMID: 8939754 Free article.

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