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Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
Musumeci D, Amato J, Zizza P, Platella C, Cosconati S, Cingolani C, Biroccio A, Novellino E, Randazzo A, Giancola C, Pagano B, Montesarchio D. Musumeci D, et al. Among authors: platella c. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1341-1352. doi: 10.1016/j.bbagen.2017.01.024. Epub 2017 Jan 24. Biochim Biophys Acta Gen Subj. 2017. PMID: 28130159
Tailoring a lead-like compound targeting multiple G-quadruplex structures.
Amato J, Platella C, Iachettini S, Zizza P, Musumeci D, Cosconati S, Pagano A, Novellino E, Biroccio A, Randazzo A, Pagano B, Montesarchio D. Amato J, et al. Among authors: platella c. Eur J Med Chem. 2019 Feb 1;163:295-306. doi: 10.1016/j.ejmech.2018.11.058. Epub 2018 Nov 27. Eur J Med Chem. 2019. PMID: 30529547
30 results