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R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling.
Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, Deng X, Wang Y, Weng X, Hu C, Yu M, Skibbe J, Dai Q, Zou D, Wu T, Yu K, Weng H, Huang H, Ferchen K, Qin X, Zhang B, Qi J, Sasaki AT, Plas DR, Bradner JE, Wei M, Marcucci G, Jiang X, Mulloy JC, Jin J, He C, Chen J. Su R, et al. Among authors: plas dr. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14. Cell. 2018. PMID: 29249359 Free PMC article.
Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia.
Liu H, Feng X, Ennis KN, Behrmann CA, Sarma P, Jiang TT, Kofuji S, Niu L, Stratton Y, Thomas HE, Yoon SO, Sasaki AT, Plas DR. Liu H, et al. Among authors: plas dr. Cell Rep. 2017 Feb 28;18(9):2088-2095. doi: 10.1016/j.celrep.2017.02.022. Cell Rep. 2017. PMID: 28249155 Free PMC article.
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.
Qing Y, Dong L, Gao L, Li C, Li Y, Han L, Prince E, Tan B, Deng X, Wetzel C, Shen C, Gao M, Chen Z, Li W, Zhang B, Braas D, Ten Hoeve J, Sanchez GJ, Chen H, Chan LN, Chen CW, Ann D, Jiang L, Müschen M, Marcucci G, Plas DR, Li Z, Su R, Chen J. Qing Y, et al. Among authors: plas dr. Mol Cell. 2021 Mar 4;81(5):922-939.e9. doi: 10.1016/j.molcel.2020.12.026. Mol Cell. 2021. PMID: 33434505 Free PMC article.
ERK2 Mediates Metabolic Stress Response to Regulate Cell Fate.
Shin S, Buel GR, Wolgamott L, Plas DR, Asara JM, Blenis J, Yoon SO. Shin S, et al. Among authors: plas dr. Mol Cell. 2015 Aug 6;59(3):382-98. doi: 10.1016/j.molcel.2015.06.020. Epub 2015 Jul 16. Mol Cell. 2015. PMID: 26190261 Free PMC article.
Reuse of Molecules for Glioblastoma Therapy.
Koehler A, Karve A, Desai P, Arbiser J, Plas DR, Qi X, Read RD, Sasaki AT, Gawali VS, Toukam DK, Bhattacharya D, Kallay L, Pomeranz Krummel DA, Sengupta S. Koehler A, et al. Among authors: plas dr. Pharmaceuticals (Basel). 2021 Jan 28;14(2):99. doi: 10.3390/ph14020099. Pharmaceuticals (Basel). 2021. PMID: 33525329 Free PMC article. Review.
70 results