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Rif2 interaction with Rad50 counteracts Tel1 functions in checkpoint signalling and DNA tethering by releasing Tel1 from MRX binding.
Nucleic Acids Res. 2024 Mar 21;52(5):2355-2371. doi: 10.1093/nar/gkad1246.
Nucleic Acids Res. 2024.
PMID: 38180815
Free PMC article.
The PP2A phosphatase counteracts the function of the 9-1-1 axis in checkpoint activation.
Casari E, Pizzul P, Rinaldi C, Gnugnoli M, Clerici M, Longhese MP.
Casari E, et al. Among authors: pizzul p.
Cell Rep. 2023 Nov 28;42(11):113360. doi: 10.1016/j.celrep.2023.113360. Epub 2023 Oct 29.
Cell Rep. 2023.
PMID: 38007689
Free article.
Item in Clipboard
The multistep path to replicative senescence onset: zooming on triggering and inhibitory events at telomeric DNA.
Pizzul P, Rinaldi C, Bonetti D.
Pizzul P, et al.
Front Cell Dev Biol. 2023 Sep 13;11:1250264. doi: 10.3389/fcell.2023.1250264. eCollection 2023.
Front Cell Dev Biol. 2023.
PMID: 37771378
Free PMC article.
Review.
Item in Clipboard
The Ku complex promotes DNA end-bridging and this function is antagonized by Tel1/ATM kinase.
Rinaldi C, Pizzul P, Casari E, Mangiagalli M, Tisi R, Longhese MP.
Rinaldi C, et al. Among authors: pizzul p.
Nucleic Acids Res. 2023 Feb 28;51(4):1783-1802. doi: 10.1093/nar/gkad062.
Nucleic Acids Res. 2023.
PMID: 36762474
Free PMC article.
Item in Clipboard
To Fix or Not to Fix: Maintenance of Chromosome Ends Versus Repair of DNA Double-Strand Breaks.
Casari E, Gnugnoli M, Rinaldi C, Pizzul P, Colombo CV, Bonetti D, Longhese MP.
Casari E, et al. Among authors: pizzul p.
Cells. 2022 Oct 14;11(20):3224. doi: 10.3390/cells11203224.
Cells. 2022.
PMID: 36291091
Free PMC article.
Review.
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The DNA damage checkpoint: A tale from budding yeast.
Pizzul P, Casari E, Gnugnoli M, Rinaldi C, Corallo F, Longhese MP.
Pizzul P, et al.
Front Genet. 2022 Sep 15;13:995163. doi: 10.3389/fgene.2022.995163. eCollection 2022.
Front Genet. 2022.
PMID: 36186482
Free PMC article.
Review.
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Sensing R-Loop-Associated DNA Damage to Safeguard Genome Stability.
Rinaldi C, Pizzul P, Longhese MP, Bonetti D.
Rinaldi C, et al. Among authors: pizzul p.
Front Cell Dev Biol. 2021 Jan 11;8:618157. doi: 10.3389/fcell.2020.618157. eCollection 2020.
Front Cell Dev Biol. 2021.
PMID: 33505970
Free PMC article.
Review.
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DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends.
Bonetti D, Rinaldi C, Vertemara J, Notaro M, Pizzul P, Tisi R, Zampella G, Longhese MP.
Bonetti D, et al. Among authors: pizzul p.
Nucleic Acids Res. 2020 Mar 18;48(5):2424-2441. doi: 10.1093/nar/gkz1203.
Nucleic Acids Res. 2020.
PMID: 31879780
Free PMC article.
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