Pitchford SC - Search Results

1

Exploring bias in platelet P2Y₁ signalling: Host defence versus haemostasis.

Pan D, Ladds G, Rahman KM, Pitchford SC. Pan D, et al. Among authors: pitchford sc. Br J Pharmacol. 2024 Feb;181(4):580-592. doi: 10.1111/bph.16191. Epub 2023 Aug 2. Br J Pharmacol. 2024. PMID: 37442808 Free PMC article. Review.

2

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

Pan D, Amison RT, Riffo-Vasquez Y, Spina D, Cleary SJ, Wakelam MJ, Page CP, Pitchford SC, Welch HC. Pan D, et al. Among authors: pitchford sc. Blood. 2015 Feb 12;125(7):1146-58. doi: 10.1182/blood-2014-07-591040. Epub 2014 Dec 23. Blood. 2015. PMID: 25538043 Free PMC article.

3

Platelets in neutrophil recruitment to sites of inflammation.

Pitchford S, Pan D, Welch HC. Pitchford S, et al. Curr Opin Hematol. 2017 Jan;24(1):23-31. doi: 10.1097/MOH.0000000000000297. Curr Opin Hematol. 2017. PMID: 27820736 Free PMC article. Review.

4

Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y₁ and P2Y₁₄ receptors in mice.

Amison RT, Arnold S, O'Shaughnessy BG, Cleary SJ, Ofoedu J, Idzko M, Page CP, Pitchford SC. Amison RT, et al. Among authors: pitchford sc. Pulm Pharmacol Ther. 2017 Aug;45:62-68. doi: 10.1016/j.pupt.2017.05.005. Epub 2017 May 6. Pulm Pharmacol Ther. 2017. PMID: 28487256

5

Diverse signalling of the platelet P2Y₁ receptor leads to a dichotomy in platelet function.

Amison RT, Jamshidi S, Rahman KM, Page CP, Pitchford SC. Amison RT, et al. Among authors: pitchford sc. Eur J Pharmacol. 2018 May 15;827:58-70. doi: 10.1016/j.ejphar.2018.03.014. Epub 2018 Mar 11. Eur J Pharmacol. 2018. PMID: 29534999

6

Pharmacological strategies for targeting platelet activation in asthma.

Pitchford S, Cleary S, Arkless K, Amison R. Pitchford S, et al. Curr Opin Pharmacol. 2019 Jun;46:55-64. doi: 10.1016/j.coph.2019.03.012. Epub 2019 Apr 23. Curr Opin Pharmacol. 2019. PMID: 31026626 Review.

7

Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology.

Cleary SJ, Pitchford SC, Amison RT, Carrington R, Robaina Cabrera CL, Magnen M, Looney MR, Gray E, Page CP. Cleary SJ, et al. Among authors: pitchford sc. Br J Pharmacol. 2020 Nov;177(21):4851-4865. doi: 10.1111/bph.15143. Epub 2020 Jul 19. Br J Pharmacol. 2020. PMID: 32462701 Free PMC article. Review.

8

The GPCR adaptor protein norbin suppresses the neutrophil-mediated immunity of mice to pneumococcal infection.

Pantarelli C, Pan D, Chetwynd S, Stark AK, Hornigold K, Machin P, Crossland L, Cleary SJ, Baker MJ, Hampson E, Mandel A, Segonds-Pichon A, Walker R, van 't Veer C, Riffo-Vasquez Y, Okkenhaug K, Pitchford S, Welch HCE. Pantarelli C, et al. Blood Adv. 2021 Aug 24;5(16):3076-3091. doi: 10.1182/bloodadvances.2020002782. Blood Adv. 2021. PMID: 34402884 Free PMC article.

9

Stimulation of platelet P2Y₁ receptors by different endogenous nucleotides leads to functional selectivity via biased signalling.

Arkless KL, Pan D, Shankar-Hari M, Amison RT, Page CP, Rahman KM, Pitchford SC. Arkless KL, et al. Among authors: pitchford sc. Br J Pharmacol. 2024 Feb;181(4):564-579. doi: 10.1111/bph.16039. Epub 2023 Feb 13. Br J Pharmacol. 2024. PMID: 36694432 Free PMC article.

10

Platelet purinergic receptors and non-thrombotic diseases.

Pitchford SC, Pan D. Pitchford SC, et al. Br J Pharmacol. 2024 Feb;181(4):513-514. doi: 10.1111/bph.16290. Epub 2023 Dec 13. Br J Pharmacol. 2024. PMID: 38093587

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