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Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.
Harb H, Benamar M, Lai PS, Contini P, Griffith JW, Crestani E, Schmitz-Abe K, Chen Q, Fong J, Marri L, Filaci G, Del Zotto G, Pishesha N, Kolifrath S, Broggi A, Ghosh S, Gelmez MY, Oktelik FB, Cetin EA, Kiykim A, Kose M, Wang Z, Cui Y, Yu XG, Li JZ, Berra L, Stephen-Victor E, Charbonnier LM, Zanoni I, Ploegh H, Deniz G, De Palma R, Chatila TA. Harb H, et al. Among authors: pishesha n. Immunity. 2021 Jun 8;54(6):1186-1199.e7. doi: 10.1016/j.immuni.2021.04.002. Epub 2021 Apr 28. Immunity. 2021. PMID: 33915108 Free PMC article.
A guide to antigen processing and presentation.
Pishesha N, Harmand TJ, Ploegh HL. Pishesha N, et al. Nat Rev Immunol. 2022 Dec;22(12):751-764. doi: 10.1038/s41577-022-00707-2. Epub 2022 Apr 13. Nat Rev Immunol. 2022. PMID: 35418563 Review.
Nanobodies as in vivo, non-invasive, imaging agents.
Harmand TJ, Islam A, Pishesha N, Ploegh HL. Harmand TJ, et al. Among authors: pishesha n. RSC Chem Biol. 2021 Mar 8;2(3):685-701. doi: 10.1039/d1cb00023c. RSC Chem Biol. 2021. PMID: 34212147 Free PMC article. Review.
An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity.
Borriello F, Poli V, Shrock E, Spreafico R, Liu X, Pishesha N, Carpenet C, Chou J, Di Gioia M, McGrath ME, Dillen CA, Barrett NA, Lacanfora L, Franco ME, Marongiu L, Iwakura Y, Pucci F, Kruppa MD, Ma Z, Lowman DW, Ensley HE, Nanishi E, Saito Y, O'Meara TR, Seo HS, Dhe-Paganon S, Dowling DJ, Frieman M, Elledge SJ, Levy O, Irvine DJ, Ploegh HL, Williams DL, Zanoni I. Borriello F, et al. Among authors: pishesha n. Cell. 2022 Feb 17;185(4):614-629.e21. doi: 10.1016/j.cell.2022.01.009. Epub 2022 Feb 10. Cell. 2022. PMID: 35148840 Free PMC article.
Site-Specific Protein Labeling via Sortase-Mediated Transpeptidation.
Antos JM, Ingram J, Fang T, Pishesha N, Truttmann MC, Ploegh HL. Antos JM, et al. Among authors: pishesha n. Curr Protoc Protein Sci. 2017 Aug 1;89:15.3.1-15.3.19. doi: 10.1002/cpps.38. Curr Protoc Protein Sci. 2017. PMID: 28762490 Free PMC article.
31 results