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Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.
Pishas KI, Drenberg CD, Taslim C, Theisen ER, Johnson KM, Saund RS, Pop IL, Crompton BD, Lawlor ER, Tirode F, Mora J, Delattre O, Beckerle MC, Callen DF, Sharma S, Lessnick SL. Pishas KI, et al. Mol Cancer Ther. 2018 Sep;17(9):1902-1916. doi: 10.1158/1535-7163.MCT-18-0373. Epub 2018 Jul 11. Mol Cancer Ther. 2018. PMID: 29997151 Free PMC article.
Mitochondrial Dysfunction Is a Driver of SP-2509 Drug Resistance in Ewing Sarcoma.
Tokarsky EJ, Crow JC, Guenther LM, Sherman J, Taslim C, Alexe G, Pishas KI, Rask G, Justis BS, Kasumova A, Stegmaier K, Lessnick SL, Theisen ER. Tokarsky EJ, et al. Among authors: pishas ki. Mol Cancer Res. 2022 Jul 6;20(7):1035-1046. doi: 10.1158/1541-7786.MCR-22-0027. Mol Cancer Res. 2022. PMID: 35298000 Free PMC article.
Recent advances in targeted therapy for Ewing sarcoma.
Pishas KI, Lessnick SL. Pishas KI, et al. F1000Res. 2016 Aug 25;5:F1000 Faculty Rev-2077. doi: 10.12688/f1000research.8631.1. eCollection 2016. F1000Res. 2016. PMID: 27635231 Free PMC article. Review.
Nutlin-3a is a potential therapeutic for ewing sarcoma.
Pishas KI, Al-Ejeh F, Zinonos I, Kumar R, Evdokiou A, Brown MP, Callen DF, Neilsen PM. Pishas KI, et al. Clin Cancer Res. 2011 Feb 1;17(3):494-504. doi: 10.1158/1078-0432.CCR-10-1587. Epub 2010 Nov 23. Clin Cancer Res. 2011. PMID: 21098696
Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma.
Patel PO, Pishas KI, Taslim C, Selich-Anderson J, Theisen ER, Lessnick SL. Patel PO, et al. Among authors: pishas ki. Oncotarget. 2019 Jun 11;10(39):3865-3878. doi: 10.18632/oncotarget.26988. eCollection 2019 Jun 11. Oncotarget. 2019. PMID: 31231465 Free PMC article.
25 results