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Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses.
O'Brien A, Loftus RM, Pisarska MM, Tobin LM, Bergin R, Wood NAW, Foley C, Mat A, Tinley FC, Bannan C, Sommerville G, Veerapen N, Besra GS, Sinclair LV, Moynagh PN, Lynch L, Finlay DK, O'Shea D, Hogan AE. O'Brien A, et al. Among authors: pisarska mm. J Immunol. 2019 Jun 15;202(12):3404-3411. doi: 10.4049/jimmunol.1801600. Epub 2019 May 10. J Immunol. 2019. PMID: 31076528
Mucosal-Associated Invariant T Cells Are Altered in Patients with Hidradenitis Suppurativa and Contribute to the Inflammatory Milieu.
Gallagher C, Mahon JM, O'Neill C, Cassidy FC, Dunbar H, De Barra C, Cadden C, Pisarska MM, Wood NAW, Masterson JC, McNamee EN, Schrumpf E, English K, O'Shea D, Tobin AM, Hogan AE. Gallagher C, et al. Among authors: pisarska mm. J Invest Dermatol. 2023 Jun;143(6):1094-1097.e2. doi: 10.1016/j.jid.2022.11.011. Epub 2022 Dec 11. J Invest Dermatol. 2023. PMID: 36516909 No abstract available.
The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis.
Kedia-Mehta N, Pisarska MM, Rollings C, O'Neill C, De Barra C, Foley C, Wood NAW, Wrigley-Kelly N, Veerapen N, Besra G, Bergin R, Jones N, O'Shea D, Sinclair LV, Hogan AE. Kedia-Mehta N, et al. Among authors: pisarska mm. Sci Signal. 2023 Apr 18;16(781):eabo2709. doi: 10.1126/scisignal.abo2709. Epub 2023 Apr 18. Sci Signal. 2023. PMID: 37071733