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UBTD1 is a mechano-regulator controlling cancer aggressiveness.
Torrino S, Roustan FR, Kaminski L, Bertero T, Pisano S, Ambrosetti D, Dufies M, Uhler JP, Lemichez E, Mettouchi A, Gesson M, Laurent K, Gaggioli C, Michiels JF, Lamaze C, Bost F, Clavel S. Torrino S, et al. Among authors: pisano s. EMBO Rep. 2019 Apr;20(4):e46570. doi: 10.15252/embr.201846570. Epub 2019 Feb 25. EMBO Rep. 2019. PMID: 30804013 Free PMC article.
Matrix Stiffening and EGFR Cooperate to Promote the Collective Invasion of Cancer Cells.
Grasset EM, Bertero T, Bozec A, Friard J, Bourget I, Pisano S, Lecacheur M, Maiel M, Bailleux C, Emelyanov A, Ilie M, Hofman P, Meneguzzi G, Duranton C, Bulavin DV, Gaggioli C. Grasset EM, et al. Among authors: pisano s. Cancer Res. 2018 Sep 15;78(18):5229-5242. doi: 10.1158/0008-5472.CAN-18-0601. Epub 2018 Jul 19. Cancer Res. 2018. PMID: 30026329
Cancer cells induce immune escape via glycocalyx changes controlled by the telomeric protein TRF2.
Cherfils-Vicini J, Iltis C, Cervera L, Pisano S, Croce O, Sadouni N, Győrffy B, Collet R, Renault VM, Rey-Millet M, Leonetti C, Zizza P, Allain F, Ghiringhelli F, Soubeiran N, Shkreli M, Vivier E, Biroccio A, Gilson E. Cherfils-Vicini J, et al. Among authors: pisano s. EMBO J. 2019 Jun 3;38(11):e100012. doi: 10.15252/embj.2018100012. Epub 2019 Apr 18. EMBO J. 2019. PMID: 31000523 Free PMC article.
A Feed-Forward Mechanosignaling Loop Confers Resistance to Therapies Targeting the MAPK Pathway in BRAF-Mutant Melanoma.
Girard CA, Lecacheur M, Ben Jouira R, Berestjuk I, Diazzi S, Prod'homme V, Mallavialle A, Larbret F, Gesson M, Schaub S, Pisano S, Audebert S, Mari B, Gaggioli C, Leucci E, Marine JC, Deckert M, Tartare-Deckert S. Girard CA, et al. Among authors: pisano s. Cancer Res. 2020 May 15;80(10):1927-1941. doi: 10.1158/0008-5472.CAN-19-2914. Epub 2020 Mar 16. Cancer Res. 2020. PMID: 32179513 Free article.
Mechano-induced cell metabolism promotes microtubule glutamylation to force metastasis.
Torrino S, Grasset EM, Audebert S, Belhadj I, Lacoux C, Haynes M, Pisano S, Abélanet S, Brau F, Chan SY, Mari B, Oldham WM, Ewald AJ, Bertero T. Torrino S, et al. Among authors: pisano s. Cell Metab. 2021 Jul 6;33(7):1342-1357.e10. doi: 10.1016/j.cmet.2021.05.009. Epub 2021 Jun 7. Cell Metab. 2021. PMID: 34102109 Free article.
Targeting Discoidin Domain Receptors DDR1 and DDR2 overcomes matrix-mediated tumor cell adaptation and tolerance to BRAF-targeted therapy in melanoma.
Berestjuk I, Lecacheur M, Carminati A, Diazzi S, Rovera C, Prod'homme V, Ohanna M, Popovic A, Mallavialle A, Larbret F, Pisano S, Audebert S, Passeron T, Gaggioli C, Girard CA, Deckert M, Tartare-Deckert S. Berestjuk I, et al. Among authors: pisano s. EMBO Mol Med. 2022 Feb 7;14(2):e11814. doi: 10.15252/emmm.201911814. Epub 2021 Dec 27. EMBO Mol Med. 2022. PMID: 34957688 Free PMC article.
Secretion of IL1 by Dedifferentiated Melanoma Cells Inhibits JAK1-STAT3-Driven Actomyosin Contractility of Lymph Node Fibroblastic Reticular Cells.
Rovera C, Berestjuk I, Lecacheur M, Tavernier C, Diazzi S, Pisano S, Irondelle M, Mallavialle A, Albrengues J, Gaggioli C, Girard CA, Passeron T, Deckert M, Tartare-Deckert S, Prod'homme V. Rovera C, et al. Among authors: pisano s. Cancer Res. 2022 May 3;82(9):1774-1788. doi: 10.1158/0008-5472.CAN-21-0501. Cancer Res. 2022. PMID: 35502542 Free article.
Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.
Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J 3rd, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY. Bertero T, et al. Among authors: pisano s. J Clin Invest. 2016 Sep 1;126(9):3313-35. doi: 10.1172/JCI86387. Epub 2016 Aug 22. J Clin Invest. 2016. PMID: 27548520 Free PMC article.
224 results