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Page 1
Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade.
Wang H, He X, Zhang L, Dong H, Huang F, Xian J, Li M, Chen W, Lu X, Pathak KV, Huang W, Li Z, Zhang L, Nguyen LXT, Yang L, Feng L, Gordon DJ, Zhang J, Pirrotte P, Chen CW, Salhotra A, Kuo YH, Horne D, Marcucci G, Sykes DB, Tiziani S, Jin H, Wang X, Li L. Wang H, et al. Among authors: pirrotte p. Blood. 2022 Jun 30;139(26):3752-3770. doi: 10.1182/blood.2021015108. Blood. 2022. PMID: 35439288 Free PMC article.
Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies.
Liefwalker DF, Ryan M, Wang Z, Pathak KV, Plaisier S, Shah V, Babra B, Dewson GS, Lai IK, Mosley AR, Fueger PT, Casey SC, Jiang L, Pirrotte P, Swaminathan S, Sears RC. Liefwalker DF, et al. Among authors: pirrotte p. Cancer Metab. 2021 Aug 16;9(1):31. doi: 10.1186/s40170-021-00263-8. Cancer Metab. 2021. PMID: 34399819 Free PMC article.
Association of Glyphosate Exposure with Blood DNA Methylation in a Cross-Sectional Study of Postmenopausal Women.
Lucia RM, Huang WL, Pathak KV, McGilvrey M, David-Dirgo V, Alvarez A, Goodman D, Masunaka I, Odegaard AO, Ziogas A, Pirrotte P, Norden-Krichmar TM, Park HL. Lucia RM, et al. Among authors: pirrotte p. Environ Health Perspect. 2022 Apr;130(4):47001. doi: 10.1289/EHP10174. Epub 2022 Apr 4. Environ Health Perspect. 2022. PMID: 35377194 Free PMC article.
ACTR5 controls CDKN2A and tumor progression in an INO80-independent manner.
Xu X, Chan AKN, Li M, Liu Q, Mattson N, Pangeni Pokharel S, Chang WH, Yuan YC, Wang J, Moore RE, Pirrotte P, Wu J, Su R, Müschen M, Rosen ST, Chen J, Yang L, Chen CW. Xu X, et al. Among authors: pirrotte p. Sci Adv. 2022 Dec 23;8(51):eadc8911. doi: 10.1126/sciadv.adc8911. Epub 2022 Dec 23. Sci Adv. 2022. PMID: 36563143 Free PMC article.
Urinary glyphosate and AMPA levels in a cross-sectional study of postmenopausal women: Associations with organic eating behavior and dietary intake.
Lucia RM, Liao X, Huang WL, Forman D, Kim A, Ziogas A, Norden-Krichmar TM, Goodman D, Alvarez A, Masunaka I, Pathak KV, McGilvrey M, Hegde AM, Pirrotte P, Park HL. Lucia RM, et al. Among authors: pirrotte p. Int J Hyg Environ Health. 2023 Jul;252:114211. doi: 10.1016/j.ijheh.2023.114211. Epub 2023 Jun 30. Int J Hyg Environ Health. 2023. PMID: 37393842 Free PMC article.
Proteomics and mathematical modeling of longitudinal CSF differentiates fast versus slow ALS progression.
Vu L, Garcia-Mansfield K, Pompeiano A, An J, David-Dirgo V, Sharma R, Venugopal V, Halait H, Marcucci G, Kuo YH, Uechi L, Rockne RC, Pirrotte P, Bowser R. Vu L, et al. Among authors: pirrotte p. Ann Clin Transl Neurol. 2023 Nov;10(11):2025-2042. doi: 10.1002/acn3.51890. Epub 2023 Aug 30. Ann Clin Transl Neurol. 2023. PMID: 37646115 Free PMC article.
Acquired miR-142 deficit in leukemic stem cells suffices to drive chronic myeloid leukemia into blast crisis.
Zhang B, Zhao D, Chen F, Frankhouser D, Wang H, Pathak KV, Dong L, Torres A, Garcia-Mansfield K, Zhang Y, Hoang DH, Chen MH, Tao S, Cho H, Liang Y, Perrotti D, Branciamore S, Rockne R, Wu X, Ghoda L, Li L, Jin J, Chen J, Yu J, Caligiuri MA, Kuo YH, Boldin M, Su R, Swiderski P, Kortylewski M, Pirrotte P, Nguyen LXT, Marcucci G. Zhang B, et al. Among authors: pirrotte p. Nat Commun. 2023 Sep 1;14(1):5325. doi: 10.1038/s41467-023-41167-z. Nat Commun. 2023. PMID: 37658085 Free PMC article.
OST-01, a natural product from Baccharis coridifolia, targets c-Myc-dependent ribogenesis in acute myeloid leukemia.
Kang H, Hoang DH, Valerio M, Pathak K, Zhang L, Buettner R, Chen F, Estrella K, Graff W, Li Z, Xie J, Horne D, Kuo YH, Zhang B, Pirrotte P, Nguyen LXT, Marcucci G. Kang H, et al. Among authors: pirrotte p. Leukemia. 2024 Mar;38(3):657-662. doi: 10.1038/s41375-024-02146-5. Epub 2024 Jan 17. Leukemia. 2024. PMID: 38233463 Free PMC article. No abstract available.
49 results