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Long non-coding RNA ACTA2-AS1 promotes ductular reaction by interacting with the p300/ELK1 complex.
J Hepatol. 2022 Apr;76(4):921-933. doi: 10.1016/j.jhep.2021.12.014. Epub 2021 Dec 23.
J Hepatol. 2022.
PMID: 34953958
Free PMC article.
Genetic or pharmacological reduction of cholangiocyte senescence improves inflammation and fibrosis in the Mdr2 -/- mouse.
Alsuraih M, O'Hara SP, Woodrum JE, Pirius NE, LaRusso NF.
Alsuraih M, et al. Among authors: pirius ne.
JHEP Rep. 2021 Jan 27;3(3):100250. doi: 10.1016/j.jhepr.2021.100250. eCollection 2021 Jun.
JHEP Rep. 2021.
PMID: 33870156
Free PMC article.
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Autophagy promotes hepatic cystogenesis in polycystic liver disease by depletion of cholangiocyte ciliogenic proteins.
Masyuk AI, Masyuk TV, Trussoni CE, Pirius NE, LaRusso NF.
Masyuk AI, et al. Among authors: pirius ne.
Hepatology. 2022 May;75(5):1110-1122. doi: 10.1002/hep.32298. Epub 2022 Feb 8.
Hepatology. 2022.
PMID: 34942041
Free PMC article.
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The Epigenetic Reader, Bromodomain Containing 2, Mediates Cholangiocyte Senescence via Interaction With ETS Proto-Oncogene 1.
Kang JH, Splinter PL, Trussoni CE, Pirius NE, Gores GJ, LaRusso NF, O'Hara SP.
Kang JH, et al. Among authors: pirius ne.
Gastroenterology. 2023 Jul;165(1):228-243.e2. doi: 10.1053/j.gastro.2023.03.235. Epub 2023 Apr 12.
Gastroenterology. 2023.
PMID: 37059338
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