Pires IS - Search Results

1

Comprehensive characterization of tense and relaxed quaternary state glutaraldehyde polymerized bovine hemoglobin as a function of cross-link density.

Gu X, Bolden-Rush C, Cuddington CT, Belcher DA, Savla C, Pires IS, Palmer AF. Gu X, et al. Among authors: pires is. Biotechnol Bioeng. 2020 Aug;117(8):2362-2376. doi: 10.1002/bit.27382. Epub 2020 Jun 12. Biotechnol Bioeng. 2020. PMID: 32472694 Free PMC article.

2

Quantification of Active Apohemoglobin Heme-Binding Sites via Dicyanohemin Incorporation.

Pires IS, Belcher DA, Palmer AF. Pires IS, et al. Biochemistry. 2017 Oct 10;56(40):5245-5259. doi: 10.1021/acs.biochem.7b00683. Epub 2017 Sep 20. Biochemistry. 2017. PMID: 28846391 Free PMC article.

3

Haptoglobin administration into the subarachnoid space prevents hemoglobin-induced cerebral vasospasm.

Hugelshofer M, Buzzi RM, Schaer CA, Richter H, Akeret K, Anagnostakou V, Mahmoudi L, Vaccani R, Vallelian F, Deuel JW, Kronen PW, Kulcsar Z, Regli L, Baek JH, Pires IS, Palmer AF, Dennler M, Humar R, Buehler PW, Kircher PR, Keller E, Schaer DJ. Hugelshofer M, et al. Among authors: pires is. J Clin Invest. 2019 Dec 2;129(12):5219-5235. doi: 10.1172/JCI130630. J Clin Invest. 2019. PMID: 31454333 Free PMC article.

4

Novel manufacturing method for producing apohemoglobin and its biophysical properties.

Pires IS, Belcher DA, Hickey R, Miller C, Badu-Tawiah AK, Baek JH, Buehler PW, Palmer AF. Pires IS, et al. Biotechnol Bioeng. 2020 Jan;117(1):125-145. doi: 10.1002/bit.27193. Epub 2019 Nov 15. Biotechnol Bioeng. 2020. PMID: 31612988

5

Controlled Polymerization and Ultrafiltration Increase the Consistency of Polymerized Hemoglobin for Use as an Oxygen Carrier.

Belcher DA, Cuddington CT, Martindale EL, Pires IS, Palmer AF. Belcher DA, et al. Among authors: pires is. Bioconjug Chem. 2020 Mar 18;31(3):605-621. doi: 10.1021/acs.bioconjchem.9b00766. Epub 2020 Jan 7. Bioconjug Chem. 2020. PMID: 31868349

6

Poly(ethylene glycol) Surface-Conjugated Apohemoglobin as a Synthetic Heme Scavenger.

Pires IS, Savla C, Palmer AF. Pires IS, et al. Biomacromolecules. 2020 Jun 8;21(6):2155-2164. doi: 10.1021/acs.biomac.0c00141. Epub 2020 Mar 30. Biomacromolecules. 2020. PMID: 32186855

7

Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme.

Munoz CJ, Pires IS, Baek JH, Buehler PW, Palmer AF, Cabrales P. Munoz CJ, et al. Among authors: pires is. Am J Physiol Heart Circ Physiol. 2020 May 1;318(5):H1296-H1307. doi: 10.1152/ajpheart.00136.2020. Epub 2020 Apr 17. Am J Physiol Heart Circ Physiol. 2020. PMID: 32302494 Free PMC article.

8

Tangential flow filtration of haptoglobin.

Pires IS, Palmer AF. Pires IS, et al. Biotechnol Prog. 2020 Sep;36(5):e3010. doi: 10.1002/btpr.3010. Epub 2020 May 13. Biotechnol Prog. 2020. PMID: 32348635

9

Anti-inflammatory effects of haptoglobin on LPS-stimulated macrophages: Role of HMGB1 signaling and implications in chronic wound healing.

Krzyszczyk P, Kang HJ, Kumar S, Meng Y, O'Reggio MD, Patel K, Pires IS, Yarmush ML, Schloss RS, Palmer AF, Berthiaume F. Krzyszczyk P, et al. Among authors: pires is. Wound Repair Regen. 2020 Jul;28(4):493-505. doi: 10.1111/wrr.12814. Epub 2020 May 19. Wound Repair Regen. 2020. PMID: 32428978 Free PMC article.

10

Apohemoglobin-haptoglobin complexes attenuate the hypertensive response to low-molecular-weight polymerized hemoglobin.

Belcher DA, Munoz C, Pires IS, Williams AT, Cabrales P, Palmer AF. Belcher DA, et al. Among authors: pires is. Blood Adv. 2020 Jun 23;4(12):2739-2750. doi: 10.1182/bloodadvances.2020002045. Blood Adv. 2020. PMID: 32559292 Free PMC article.

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