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The History of Anti-Trypanosome Vaccine Development Shows That Highly Immunogenic and Exposed Pathogen-Derived Antigens Are Not Necessarily Good Target Candidates: Enolase and ISG75 as Examples.
Magez S, Li Z, Nguyen HTT, Pinto Torres JE, Van Wielendaele P, Radwanska M, Began J, Zoll S, Sterckx YG. Magez S, et al. Among authors: pinto torres je. Pathogens. 2021 Aug 19;10(8):1050. doi: 10.3390/pathogens10081050. Pathogens. 2021. PMID: 34451514 Free PMC article.
Q586B2 is a crucial virulence factor during the early stages of Trypanosoma brucei infection that is conserved amongst trypanosomatids.
Stijlemans B, De Baetselier P, Van Molle I, Lecordier L, Hendrickx E, Romão E, Vincke C, Baetens W, Schoonooghe S, Hassanzadeh-Ghassabeh G, Korf H, Wallays M, Pinto Torres JE, Perez-Morga D, Brys L, Campetella O, Leguizamón MS, Claes M, Hendrickx S, Mabille D, Caljon G, Remaut H, Roelants K, Magez S, Van Ginderachter JA, De Trez C. Stijlemans B, et al. Among authors: pinto torres je. Nat Commun. 2024 Feb 27;15(1):1779. doi: 10.1038/s41467-024-46067-4. Nat Commun. 2024. PMID: 38413606 Free PMC article.