Pinney KG - Search Results

1

Synthesis and Biological Evaluation of Benzocyclooctene-based and Indene-based Anticancer Agents that Function as Inhibitors of Tubulin Polymerization.

Herdman CA, Strecker TE, Tanpure RP, Chen Z, Winters A, Gerberich J, Liu L, Hamel E, Mason RP, Chaplin DJ, Trawick ML, Pinney KG. Herdman CA, et al. Among authors: pinney kg. Medchemcomm. 2016 Dec 1;7(12):2418-2427. doi: 10.1039/C6MD00459H. Epub 2016 Sep 22. Medchemcomm. 2016. PMID: 28217276 Free PMC article.

2

A new anti-tubulin agent containing the benzo[b]thiophene ring system.

Pinney KG, Bounds AD, Dingeman KM, Mocharla VP, Pettit GR, Bai R, Hamel E. Pinney KG, et al. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1081-6. doi: 10.1016/s0960-894x(99)00143-2. Bioorg Med Chem Lett. 1999. PMID: 10328289

3

Synthesis and biological evaluation of aryl azide derivatives of combretastatin A-4 as molecular probes for tubulin.

Pinney KG, Mejia MP, Villalobos VM, Rosenquist BE, Pettit GR, Verdier-Pinard P, Hamel E. Pinney KG, et al. Bioorg Med Chem. 2000 Oct;8(10):2417-25. doi: 10.1016/s0968-0896(00)00176-0. Bioorg Med Chem. 2000. PMID: 11058036

4

Preparation of new anti-tubulin ligands through a dual-mode, addition-elimination reaction to a bromo-substituted alpha, beta-unsaturated sulfoxide.

Chen Z, Mocharla VP, Farmer JM, Pettit GR, Hamel E, Pinney KG. Chen Z, et al. Among authors: pinney kg. J Org Chem. 2000 Dec 15;65(25):8811-5. doi: 10.1021/jo0004761. J Org Chem. 2000. PMID: 11112609 No abstract available.

5

Synthesis, in vitro, and in vivo evaluation of phosphate ester derivatives of combretastatin A-4.

Hadimani MB, Hua J, Jonklaas MD, Kessler RJ, Sheng Y, Olivares A, Tanpure RP, Weiser A, Zhang J, Edvardsen K, Kane RR, Pinney KG. Hadimani MB, et al. Among authors: pinney kg. Bioorg Med Chem Lett. 2003 May 5;13(9):1505-8. doi: 10.1016/s0960-894x(03)00206-3. Bioorg Med Chem Lett. 2003. PMID: 12699742

6

Oxi4503, a novel vascular targeting agent: effects on blood flow and antitumor activity in comparison to combretastatin A-4 phosphate.

Hua J, Sheng Y, Pinney KG, Garner CM, Kane RR, Prezioso JA, Pettit GR, Chaplin DJ, Edvardsen K. Hua J, et al. Among authors: pinney kg. Anticancer Res. 2003 Mar-Apr;23(2B):1433-40. Anticancer Res. 2003. PMID: 12820406

7

Combretastatin family member OXI4503 induces tumor vascular collapse through the induction of endothelial apoptosis.

Sheng Y, Hua J, Pinney KG, Garner CM, Kane RR, Prezioso JA, Chaplin DJ, Edvardsen K. Sheng Y, et al. Among authors: pinney kg. Int J Cancer. 2004 Sep 10;111(4):604-10. doi: 10.1002/ijc.20297. Int J Cancer. 2004. PMID: 15239140 Free article.

8

Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents.

Monk KA, Siles R, Hadimani MB, Mugabe BE, Ackley JF, Studerus SW, Edvardsen K, Trawick ML, Garner CM, Rhodes MR, Pettit GR, Pinney KG. Monk KA, et al. Among authors: pinney kg. Bioorg Med Chem. 2006 May 1;14(9):3231-44. doi: 10.1016/j.bmc.2005.12.033. Epub 2006 Jan 25. Bioorg Med Chem. 2006. PMID: 16442292

9

Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas' disease.

Siles R, Chen SE, Zhou M, Pinney KG, Trawick ML. Siles R, et al. Among authors: pinney kg. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4405-9. doi: 10.1016/j.bmcl.2006.05.041. Epub 2006 Jun 15. Bioorg Med Chem Lett. 2006. PMID: 16781147

10

Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents.

Siles R, Ackley JF, Hadimani MB, Hall JJ, Mugabe BE, Guddneppanavar R, Monk KA, Chapuis JC, Pettit GR, Chaplin DJ, Edvardsen K, Trawick ML, Garner CM, Pinney KG. Siles R, et al. Among authors: pinney kg. J Nat Prod. 2008 Mar;71(3):313-20. doi: 10.1021/np070377j. Epub 2008 Feb 28. J Nat Prod. 2008. PMID: 18303849

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