Pinney KG - Search Results

1

Application of the McMurry coupling reaction in the synthesis of tri- and tetra-arylethylene analogues as potential cancer chemotherapeutic agents.

Tanpure RP, Harkrider AR, Strecker TE, Hamel E, Trawick ML, Pinney KG. Tanpure RP, et al. Among authors: pinney kg. Bioorg Med Chem. 2009 Oct 1;17(19):6993-7001. doi: 10.1016/j.bmc.2009.08.011. Epub 2009 Aug 12. Bioorg Med Chem. 2009. PMID: 19733085 Free PMC article.

2

A new anti-tubulin agent containing the benzo[b]thiophene ring system.

Pinney KG, Bounds AD, Dingeman KM, Mocharla VP, Pettit GR, Bai R, Hamel E. Pinney KG, et al. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1081-6. doi: 10.1016/s0960-894x(99)00143-2. Bioorg Med Chem Lett. 1999. PMID: 10328289

3

Synthesis and biological evaluation of aryl azide derivatives of combretastatin A-4 as molecular probes for tubulin.

Pinney KG, Mejia MP, Villalobos VM, Rosenquist BE, Pettit GR, Verdier-Pinard P, Hamel E. Pinney KG, et al. Bioorg Med Chem. 2000 Oct;8(10):2417-25. doi: 10.1016/s0968-0896(00)00176-0. Bioorg Med Chem. 2000. PMID: 11058036

4

Preparation of new anti-tubulin ligands through a dual-mode, addition-elimination reaction to a bromo-substituted alpha, beta-unsaturated sulfoxide.

Chen Z, Mocharla VP, Farmer JM, Pettit GR, Hamel E, Pinney KG. Chen Z, et al. Among authors: pinney kg. J Org Chem. 2000 Dec 15;65(25):8811-5. doi: 10.1021/jo0004761. J Org Chem. 2000. PMID: 11112609 No abstract available.

5

Synthesis, in vitro, and in vivo evaluation of phosphate ester derivatives of combretastatin A-4.

Hadimani MB, Hua J, Jonklaas MD, Kessler RJ, Sheng Y, Olivares A, Tanpure RP, Weiser A, Zhang J, Edvardsen K, Kane RR, Pinney KG. Hadimani MB, et al. Among authors: pinney kg. Bioorg Med Chem Lett. 2003 May 5;13(9):1505-8. doi: 10.1016/s0960-894x(03)00206-3. Bioorg Med Chem Lett. 2003. PMID: 12699742

6

Synthesis and biological evaluation of 2-(4-fluorophenoxy)-2-phenyl-ethyl piperazines as serotonin-selective reuptake inhibitors with a potentially improved adverse reaction profile.

Dorsey JM, Miranda MG, Cozzi NV, Pinney KG. Dorsey JM, et al. Among authors: pinney kg. Bioorg Med Chem. 2004 Mar 15;12(6):1483-91. doi: 10.1016/j.bmc.2003.12.021. Bioorg Med Chem. 2004. PMID: 15018922

7

Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents.

Monk KA, Siles R, Hadimani MB, Mugabe BE, Ackley JF, Studerus SW, Edvardsen K, Trawick ML, Garner CM, Rhodes MR, Pettit GR, Pinney KG. Monk KA, et al. Among authors: pinney kg. Bioorg Med Chem. 2006 May 1;14(9):3231-44. doi: 10.1016/j.bmc.2005.12.033. Epub 2006 Jan 25. Bioorg Med Chem. 2006. PMID: 16442292

8

Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas' disease.

Siles R, Chen SE, Zhou M, Pinney KG, Trawick ML. Siles R, et al. Among authors: pinney kg. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4405-9. doi: 10.1016/j.bmcl.2006.05.041. Epub 2006 Jun 15. Bioorg Med Chem Lett. 2006. PMID: 16781147

9

Combretastatin dinitrogen-substituted stilbene analogues as tubulin-binding and vascular-disrupting agents.

Siles R, Ackley JF, Hadimani MB, Hall JJ, Mugabe BE, Guddneppanavar R, Monk KA, Chapuis JC, Pettit GR, Chaplin DJ, Edvardsen K, Trawick ML, Garner CM, Pinney KG. Siles R, et al. Among authors: pinney kg. J Nat Prod. 2008 Mar;71(3):313-20. doi: 10.1021/np070377j. Epub 2008 Feb 28. J Nat Prod. 2008. PMID: 18303849

10

Design, synthesis, biochemical, and biological evaluation of nitrogen-containing trifluoro structural modifications of combretastatin A-4.

Hall JJ, Sriram M, Strecker TE, Tidmore JK, Jelinek CJ, Kumar GD, Hadimani MB, Pettit GR, Chaplin DJ, Trawick ML, Pinney KG. Hall JJ, et al. Among authors: pinney kg. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5146-9. doi: 10.1016/j.bmcl.2008.07.070. Epub 2008 Jul 24. Bioorg Med Chem Lett. 2008. PMID: 18710804

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