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Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors.
Science. 2023 Nov 10;382(6671):eabo7201. doi: 10.1126/science.abo7201. Epub 2023 Nov 10.
Science. 2023.
PMID: 37943932
Free PMC article.
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.
Jansen J, Reimer KC, Nagai JS, Varghese FS, Overheul GJ, de Beer M, Roverts R, Daviran D, Fermin LAS, Willemsen B, Beukenboom M, Djudjaj S, von Stillfried S, van Eijk LE, Mastik M, Bulthuis M, Dunnen WD, van Goor H, Hillebrands JL, Triana SH, Alexandrov T, Timm MC, van den Berge BT, van den Broek M, Nlandu Q, Heijnert J, Bindels EMJ, Hoogenboezem RM, Mooren F, Kuppe C, Miesen P, Grünberg K, Ijzermans T, Steenbergen EJ, Czogalla J, Schreuder MF, Sommerdijk N, Akiva A, Boor P, Puelles VG, Floege J, Huber TB; COVID Moonshot consortium; van Rij RP, Costa IG, Schneider RK, Smeets B, Kramann R.
Jansen J, et al.
Cell Stem Cell. 2022 Feb 3;29(2):217-231.e8. doi: 10.1016/j.stem.2021.12.010. Epub 2021 Dec 25.
Cell Stem Cell. 2022.
PMID: 35032430
Free PMC article.
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Molecular dynamics simulation and in vitro evaluation of herb-drug interactions involving dietary polyphenols and CDK inhibitors in breast cancer chemotherapy.
Patil PH, Birangal S, Shenoy GG, Rao M, Kadari S, Wankhede A, Rastogi H, Sharma T, Pinjari J, Puralae Channabasavaiah J.
Patil PH, et al. Among authors: pinjari j.
Phytother Res. 2022 Oct;36(10):3988-4001. doi: 10.1002/ptr.7547. Epub 2022 Jul 2.
Phytother Res. 2022.
PMID: 35778986
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Inhibition of Cytochrome P450 Enzyme and Drug-Drug Interaction Potential of Acid Reducing Agents Used in Management of CDK Inhibitors for Breast Cancer Chemotherapy.
Patil PH, Jagadish PC, Fatima F, Birangal S, Shenoy GG, Rao M, Farooqui J, Rastogi H, Sharma T, Pinjari J.
Patil PH, et al. Among authors: pinjari j.
Curr Drug Metab. 2022;23(2):137-149. doi: 10.2174/1389200223666220218090948.
Curr Drug Metab. 2022.
PMID: 35184709
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In vitro metabolism, disposition, preclinical pharmacokinetics and prediction of human pharmacokinetics of DNDI-VL-2098, a potential oral treatment for Visceral Leishmaniasis.
Mukkavilli R, Pinjari J, Patel B, Sengottuvelan S, Mondal S, Gadekar A, Verma M, Patel J, Pothuri L, Chandrashekar G, Koiram P, Harisudhan T, Moinuddin A, Launay D, Vachharajani N, Ramanathan V, Martin D.
Mukkavilli R, et al. Among authors: pinjari j.
Eur J Pharm Sci. 2014 Dec 18;65:147-55. doi: 10.1016/j.ejps.2014.09.006. Epub 2014 Sep 27.
Eur J Pharm Sci. 2014.
PMID: 25261338
Free article.
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Design, synthesis and biological evaluation of 2-substituted quinolines as potential antileishmanial agents.
Gopinath VS, Pinjari J, Dere RT, Verma A, Vishwakarma P, Shivahare R, Moger M, Kumar Goud PS, Ramanathan V, Bose P, Rao MV, Gupta S, Puri SK, Launay D, Martin D.
Gopinath VS, et al. Among authors: pinjari j.
Eur J Med Chem. 2013 Nov;69:527-36. doi: 10.1016/j.ejmech.2013.08.028. Epub 2013 Sep 15.
Eur J Med Chem. 2013.
PMID: 24095747
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Validation of 96-well equilibrium dialysis with non-radiolabeled drug for definitive measurement of protein binding and application to clinical development of highly-bound drugs.
Zamek-Gliszczynski MJ, Ruterbories KJ, Ajamie RT, Wickremsinhe ER, Pothuri L, Rao MV, Basavanakatti VN, Pinjari J, Ramanathan VK, Chaudhary AK.
Zamek-Gliszczynski MJ, et al. Among authors: pinjari j.
J Pharm Sci. 2011 Jun;100(6):2498-507. doi: 10.1002/jps.22452. Epub 2011 Jan 6.
J Pharm Sci. 2011.
PMID: 21213309
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