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Identification of a potential lead structure for designing new antimicrobials to treat infections caused by Staphylococcus epidermidis-resistant strains.
Pinheiro LC, Abreu PA, Afonso IF, Leal B, Corrêa LC, Borges JC, Marques IP, Lourenço AL, Sathler P, dos Santos AL, Medeiros CA, Cabral LM, Júnior ML, Romeiro GA, Ferreira VF, Rodrigues CR, Castro HC, Bernardino AM. Pinheiro LC, et al. Curr Microbiol. 2008 Nov;57(5):463-8. doi: 10.1007/s00284-008-9234-5. Epub 2008 Sep 23. Curr Microbiol. 2008. PMID: 18810543
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
Silveira FF, de Souza JO, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Silveira FF, et al. Among authors: pinheiro lcs. Eur J Med Chem. 2021 Jan 1;209:112941. doi: 10.1016/j.ejmech.2020.112941. Epub 2020 Oct 21. Eur J Med Chem. 2021. PMID: 33158577
Discovery of new piperaquine hybrid analogs linked by triazolopyrimidine and pyrazolopyrimidine scaffolds with antiplasmodial and transmission blocking activities.
Feitosa LM, Franca RRF, Ferreira MLG, Aguiar ACC, de Souza GE, Maluf SEC, de Souza JO, Zapata L, Duarte D, Morais I, Nogueira F, Nonato MC, Pinheiro LCS, Guido RVC, Boechat N. Feitosa LM, et al. Among authors: pinheiro lcs. Eur J Med Chem. 2024 Mar 5;267:116163. doi: 10.1016/j.ejmech.2024.116163. Epub 2024 Jan 25. Eur J Med Chem. 2024. PMID: 38290351
SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series.
Bernardino AM, Castro HC, Frugulhetti IC, Loureiro NI, Azevedo AR, Pinheiro LC, Souza TM, Giongo V, Passamani F, Magalhães UO, Albuquerque MG, Cabral LM, Rodrigues CR. Bernardino AM, et al. Bioorg Med Chem. 2008 Jan 1;16(1):313-21. doi: 10.1016/j.bmc.2007.09.032. Epub 2007 Sep 22. Bioorg Med Chem. 2008. PMID: 17937990
Anti-Plasmodium falciparum activity of quinoline-sulfonamide hybrids.
Pinheiro LC, Boechat N, Ferreira Mde L, Júnior CC, Jesus AM, Leite MM, Souza NB, Krettli AU. Pinheiro LC, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5979-84. doi: 10.1016/j.bmc.2015.06.056. Epub 2015 Jul 2. Bioorg Med Chem. 2015. PMID: 26190461
23 results