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N-(4-Chloro-phen-yl)-5-(4,5-dihydro-1H-imidazol-2-yl)thieno[2,3-b]pyridin-4-amine.
Bernardino AM, Pinheiro LC, Tiekink ER, Wardell JL, Wardell SM. Bernardino AM, et al. Among authors: pinheiro lc. Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2135-6. doi: 10.1107/S160053681202658X. Epub 2012 Jun 20. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22798811 Free PMC article.
4-(3-Fluoro-anilino)thieno[2,3-b]pyridine-6-carb-oxy-lic acid.
Pinheiro LC, Bernardino AM, Wardell SM, Wardell JL, Tiekink ER. Pinheiro LC, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2217-8. doi: 10.1107/S1600536812027195. Epub 2012 Jun 27. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22798877 Free PMC article.
SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series.
Bernardino AM, Castro HC, Frugulhetti IC, Loureiro NI, Azevedo AR, Pinheiro LC, Souza TM, Giongo V, Passamani F, Magalhães UO, Albuquerque MG, Cabral LM, Rodrigues CR. Bernardino AM, et al. Among authors: pinheiro lc. Bioorg Med Chem. 2008 Jan 1;16(1):313-21. doi: 10.1016/j.bmc.2007.09.032. Epub 2007 Sep 22. Bioorg Med Chem. 2008. PMID: 17937990
Identification of a potential lead structure for designing new antimicrobials to treat infections caused by Staphylococcus epidermidis-resistant strains.
Pinheiro LC, Abreu PA, Afonso IF, Leal B, Corrêa LC, Borges JC, Marques IP, Lourenço AL, Sathler P, dos Santos AL, Medeiros CA, Cabral LM, Júnior ML, Romeiro GA, Ferreira VF, Rodrigues CR, Castro HC, Bernardino AM. Pinheiro LC, et al. Curr Microbiol. 2008 Nov;57(5):463-8. doi: 10.1007/s00284-008-9234-5. Epub 2008 Sep 23. Curr Microbiol. 2008. PMID: 18810543
New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents.
Boechat N, Pinheiro LC, Silva TS, Aguiar AC, Carvalho AS, Bastos MM, Costa CC, Pinheiro S, Pinto AC, Mendonça JS, Dutra KD, Valverde AL, Santos-Filho OA, Ceravolo IP, Krettli AU. Boechat N, et al. Among authors: pinheiro s, pinheiro lc. Molecules. 2012 Jul 10;17(7):8285-302. doi: 10.3390/molecules17078285. Molecules. 2012. PMID: 22781441 Free PMC article.
Novel selective inhibitor of Leishmania (Leishmania) amazonensis arginase.
da Silva ER, Boechat N, Pinheiro LC, Bastos MM, Costa CC, Bartholomeu JC, da Costa TH. da Silva ER, et al. Among authors: pinheiro lc. Chem Biol Drug Des. 2015 Nov;86(5):969-78. doi: 10.1111/cbdd.12566. Epub 2015 May 14. Chem Biol Drug Des. 2015. PMID: 25845502
Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
Silveira FF, de Souza JO, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Silveira FF, et al. Eur J Med Chem. 2021 Jan 1;209:112941. doi: 10.1016/j.ejmech.2020.112941. Epub 2020 Oct 21. Eur J Med Chem. 2021. PMID: 33158577
249 results