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Defensins as anti-inflammatory compounds and mucosal adjuvants.
Kohlgraf KG, Pingel LC, Dietrich DE, Brogden KA. Kohlgraf KG, et al. Among authors: pingel lc. Future Microbiol. 2010 Jan;5(1):99-113. doi: 10.2217/fmb.09.104. Future Microbiol. 2010. PMID: 20020832 Free PMC article. Review.
Human beta-defensin 3 binds to hemagglutinin B (rHagB), a non-fimbrial adhesin from Porphyromonas gingivalis, and attenuates a pro-inflammatory cytokine response.
Pingel LC, Kohlgraf KG, Hansen CJ, Eastman CG, Dietrich DE, Burnell KK, Srikantha RN, Xiao X, Bélanger M, Progulske-Fox A, Cavanaugh JE, Guthmiller JM, Johnson GK, Joly S, Kurago ZB, Dawson DV, Brogden KA. Pingel LC, et al. Immunol Cell Biol. 2008 Nov-Dec;86(8):643-9. doi: 10.1038/icb.2008.56. Epub 2008 Aug 19. Immunol Cell Biol. 2008. PMID: 18711400