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Molecular profiling identifies targeted therapy opportunities in pediatric solid cancer.
Church AJ, Corson LB, Kao PC, Imamovic-Tuco A, Reidy D, Doan D, Kang W, Pinto N, Maese L, Laetsch TW, Kim A, Colace SI, Macy ME, Applebaum MA, Bagatell R, Sabnis AJ, Weiser DA, Glade-Bender JL, Homans AC, Hipps J, Harris H, Manning D, Al-Ibraheemi A, Li Y, Gupta H, Cherniack AD, Lo YC, Strand GR, Lee LA, Pinches RS, Lazo De La Vega L, Harden MV, Lennon NJ, Choi S, Comeau H, Harris MH, Forrest SJ, Clinton CM, Crompton BD, Kamihara J, MacConaill LE, Volchenboum SL, Lindeman NI, Van Allen E, DuBois SG, London WB, Janeway KA. Church AJ, et al. Among authors: pinches rs. Nat Med. 2022 Aug;28(8):1581-1589. doi: 10.1038/s41591-022-01856-6. Epub 2022 Jun 23. Nat Med. 2022. PMID: 35739269 Free PMC article.
Genomic and Immunologic Characterization of INI1-Deficient Pediatric Cancers.
Forrest SJ, Al-Ibraheemi A, Doan D, Ward A, Clinton CM, Putra J, Pinches RS, Kadoch C, Chi SN, DuBois SG, Leavey PJ, LeBoeuf NR, Mullen E, Collins N, Church AJ, Janeway KA. Forrest SJ, et al. Among authors: pinches rs. Clin Cancer Res. 2020 Jun 15;26(12):2882-2890. doi: 10.1158/1078-0432.CCR-19-3089. Epub 2020 Mar 2. Clin Cancer Res. 2020. PMID: 32122923 Free PMC article.
DICER1-associated central nervous system sarcoma in children: comprehensive clinicopathologic and genetic analysis of a newly described rare tumor.
Kamihara J, Paulson V, Breen MA, Laetsch TW, Rakheja D, Shulman DS, Schoettler ML, Clinton CM, Ward A, Reidy D, Pinches RS, Weiser DA, Mullen EA, Schienda J, Meyers PA, DuBois SG, Nowak JA, Foulkes WD, Schultz KAP, Janeway KA, Vargas SO, Church AJ. Kamihara J, et al. Among authors: pinches rs. Mod Pathol. 2020 Oct;33(10):1910-1921. doi: 10.1038/s41379-020-0516-1. Epub 2020 Apr 14. Mod Pathol. 2020. PMID: 32291395 Free article.
Making the most of small samples: Optimization of tissue allocation of pediatric solid tumors for clinical and research use.
Pinches RS, Clinton CM, Ward A, Meyer SC, Al-Ibraheemi A, Forrest SJ, Strand GR, Detert H, Piche-Schulman A, Gill K, Restrepo T, Tavares Proulx R, Perez-Atayde AR, Vargas SO, Shaikh R, Weldon C, Alexandrescu S, Hong AL, O'Neill AF, Hollowell M, Harris MH, Janeway KA, Crompton BD, Church AJ. Pinches RS, et al. Pediatr Blood Cancer. 2020 Sep;67(9):e28326. doi: 10.1002/pbc.28326. Epub 2020 Jul 15. Pediatr Blood Cancer. 2020. PMID: 32667141
Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice.
Garcia Castro DR, Mazuk JR, Heine EM, Simpson D, Pinches RS, Lozzi C, Hoffman K, Morrin P, Mathis D, Lebedev MV, Nissley E, Han KH, Farmer T, Merry DE, Tong Q, Pennuto M, Montie HL. Garcia Castro DR, et al. Among authors: pinches rs. iScience. 2023 Jul 22;26(8):107375. doi: 10.1016/j.isci.2023.107375. eCollection 2023 Aug 18. iScience. 2023. PMID: 37599829 Free PMC article.