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Mesoderm-derived PDGFRA+ cells regulate the emergence of hematopoietic stem cells in the dorsal aorta.
Chandrakanthan V, Rorimpandey P, Zanini F, Chacon D, Olivier J, Joshi S, Kang YC, Knezevic K, Huang Y, Qiao Q, Oliver RA, Unnikrishnan A, Carter DR, Lee B, Brownlee C, Power C, Brink R, Mendez-Ferrer S, Enikolopov G, Walsh W, Göttgens B, Taoudi S, Beck D, Pimanda JE. Chandrakanthan V, et al. Among authors: pimanda je. Nat Cell Biol. 2022 Aug;24(8):1211-1225. doi: 10.1038/s41556-022-00955-3. Epub 2022 Jul 28. Nat Cell Biol. 2022. PMID: 35902769 Free PMC article.
The paralogous hematopoietic regulators Lyl1 and Scl are coregulated by Ets and GATA factors, but Lyl1 cannot rescue the early Scl-/- phenotype.
Chan WY, Follows GA, Lacaud G, Pimanda JE, Landry JR, Kinston S, Knezevic K, Piltz S, Donaldson IJ, Gambardella L, Sablitzky F, Green AR, Kouskoff V, Göttgens B. Chan WY, et al. Among authors: pimanda je. Blood. 2007 Mar 1;109(5):1908-16. doi: 10.1182/blood-2006-05-023226. Epub 2006 Oct 19. Blood. 2007. PMID: 17053063 Free article.
Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.
Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WY, Wilson NK, Landry JR, Wood AD, Kolb-Kokocinski A, Green AR, Tannahill D, Lacaud G, Kouskoff V, Göttgens B. Pimanda JE, et al. Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17692-7. doi: 10.1073/pnas.0707045104. Epub 2007 Oct 25. Proc Natl Acad Sci U S A. 2007. PMID: 17962413 Free PMC article.
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver.
Landry JR, Kinston S, Knezevic K, de Bruijn MF, Wilson N, Nottingham WT, Peitz M, Edenhofer F, Pimanda JE, Ottersbach K, Göttgens B. Landry JR, et al. Among authors: pimanda je. Blood. 2008 Mar 15;111(6):3005-14. doi: 10.1182/blood-2007-07-098830. Epub 2008 Jan 9. Blood. 2008. PMID: 18184866 Free article.
Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code.
Pimanda JE, Chan WY, Wilson NK, Smith AM, Kinston S, Knezevic K, Janes ME, Landry JR, Kolb-Kokocinski A, Frampton J, Tannahill D, Ottersbach K, Follows GA, Lacaud G, Kouskoff V, Göttgens B. Pimanda JE, et al. Blood. 2008 Dec 1;112(12):4512-22. doi: 10.1182/blood-2008-05-157560. Epub 2008 Sep 19. Blood. 2008. PMID: 18805961 Free PMC article.
106 results