Pihlavisto M - Search Results

1

Novel hydrazine molecules as tools to understand the flexibility of vascular adhesion protein-1 ligand-binding site: toward more selective inhibitors.

Nurminen EM, Pihlavisto M, Lázár L, Pentikäinen U, Fülöp F, Pentikäinen OT. Nurminen EM, et al. Among authors: pihlavisto m. J Med Chem. 2011 Apr 14;54(7):2143-54. doi: 10.1021/jm200059p. Epub 2011 Mar 15. J Med Chem. 2011. PMID: 21405023 Free article.

2

Synthesis, in vitro activity, and three-dimensional quantitative structure-activity relationship of novel hydrazine inhibitors of human vascular adhesion protein-1.

Nurminen EM, Pihlavisto M, Lázár L, Szakonyi Z, Pentikäinen U, Fülöp F, Pentikäinen OT. Nurminen EM, et al. Among authors: pihlavisto m. J Med Chem. 2010 Sep 9;53(17):6301-15. doi: 10.1021/jm100337z. J Med Chem. 2010. PMID: 20690686

3

Novel pyridazinone inhibitors for vascular adhesion protein-1 (VAP-1): old target-new inhibition mode.

Bligt-Lindén E, Pihlavisto M, Szatmári I, Otwinowski Z, Smith DJ, Lázár L, Fülöp F, Salminen TA. Bligt-Lindén E, et al. Among authors: pihlavisto m. J Med Chem. 2013 Dec 27;56(24):9837-48. doi: 10.1021/jm401372d. Epub 2013 Dec 13. J Med Chem. 2013. PMID: 24304424 Free PMC article.

4

Vascular amine oxidases are needed for leukocyte extravasation into inflamed joints in vivo.

Marttila-Ichihara F, Smith DJ, Stolen C, Yegutkin GG, Elima K, Mercier N, Kiviranta R, Pihlavisto M, Alaranta S, Pentikäinen U, Pentikäinen O, Fülöp F, Jalkanen S, Salmi M. Marttila-Ichihara F, et al. Among authors: pihlavisto m. Arthritis Rheum. 2006 Sep;54(9):2852-62. doi: 10.1002/art.22061. Arthritis Rheum. 2006. PMID: 16947396 Free article.

5

Novel α2β1 integrin inhibitors reveal that integrin binding to collagen under shear stress conditions does not require receptor preactivation.

Nissinen L, Koivunen J, Käpylä J, Salmela M, Nieminen J, Jokinen J, Sipilä K, Pihlavisto M, Pentikäinen OT, Marjamäki A, Heino J. Nissinen L, et al. Among authors: pihlavisto m. J Biol Chem. 2012 Dec 28;287(53):44694-702. doi: 10.1074/jbc.M111.309450. Epub 2012 Nov 6. J Biol Chem. 2012. PMID: 23132859 Free PMC article.

6

Fluorescent small molecule probe to modulate and explore α2β1 integrin function.

Koivunen JT, Nissinen L, Käpylä J, Jokinen J, Pihlavisto M, Marjamäki A, Heino J, Huuskonen J, Pentikäinen OT. Koivunen JT, et al. Among authors: pihlavisto m. J Am Chem Soc. 2011 Sep 21;133(37):14558-61. doi: 10.1021/ja206086c. Epub 2011 Aug 30. J Am Chem Soc. 2011. PMID: 21863823

7

Crystallization and preliminary X-ray analysis of the human vascular adhesion protein-1.

Nymalm Y, Kidron H, Söderholm A, Viitanen L, Kaukonen K, Pihlavisto M, Smith D, Veromaa T, Airenne TT, Johnson MS, Salminen TA. Nymalm Y, et al. Among authors: pihlavisto m. Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1288-90. doi: 10.1107/s090744490300979x. Epub 2003 Jun 27. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12832789

8

Identification of two imidazole binding sites and key residues for substrate specificity in human primary amine oxidase AOC3.

Elovaara H, Kidron H, Parkash V, Nymalm Y, Bligt E, Ollikka P, Smith DJ, Pihlavisto M, Salmi M, Jalkanen S, Salminen TA. Elovaara H, et al. Among authors: pihlavisto m. Biochemistry. 2011 Jun 21;50(24):5507-20. doi: 10.1021/bi200117z. Epub 2011 May 27. Biochemistry. 2011. PMID: 21585208

9

Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1).

Koskinen K, Vainio PJ, Smith DJ, Pihlavisto M, Ylä-Herttuala S, Jalkanen S, Salmi M. Koskinen K, et al. Among authors: pihlavisto m. Blood. 2004 May 1;103(9):3388-95. doi: 10.1182/blood-2003-09-3275. Epub 2004 Jan 15. Blood. 2004. PMID: 14726375 Free article.

10

Crystal structure of the human vascular adhesion protein-1: unique structural features with functional implications.

Airenne TT, Nymalm Y, Kidron H, Smith DJ, Pihlavisto M, Salmi M, Jalkanen S, Johnson MS, Salminen TA. Airenne TT, et al. Among authors: pihlavisto m. Protein Sci. 2005 Aug;14(8):1964-74. doi: 10.1110/ps.051438105. Protein Sci. 2005. PMID: 16046623 Free PMC article.

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