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Procaspase-Activating Compound-1 Synergizes with TRAIL to Induce Apoptosis in Established Granulosa Cell Tumor Cell Line (KGN) and Explanted Patient Granulosa Cell Tumor Cells In Vitro.
Crosley P, Farkkila A, Jenner AL, Burlot C, Cardinal O, Potts KG, Agopsowicz K, Pihlajoki M, Heikinheimo M, Craig M, Fu Y, Hitt MM. Crosley P, et al. Among authors: pihlajoki m. Int J Mol Sci. 2021 Apr 29;22(9):4699. doi: 10.3390/ijms22094699. Int J Mol Sci. 2021. PMID: 33946730 Free PMC article.
Serum vascular endothelial growth factor A (VEGF) is elevated in patients with ovarian granulosa cell tumor (GCT), and VEGF inhibition by bevacizumab induces apoptosis in GCT in vitro.
Färkkilä A, Pihlajoki M, Tauriala H, Bützow R, Leminen A, Unkila-Kallio L, Heikinheimo M, Anttonen M. Färkkilä A, et al. Among authors: pihlajoki m. J Clin Endocrinol Metab. 2011 Dec;96(12):E1973-81. doi: 10.1210/jc.2011-1812. Epub 2011 Oct 12. J Clin Endocrinol Metab. 2011. PMID: 21994955
GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.
Krachulec J, Vetter M, Schrade A, Löbs AK, Bielinska M, Cochran R, Kyrönlahti A, Pihlajoki M, Parviainen H, Jay PY, Heikinheimo M, Wilson DB. Krachulec J, et al. Among authors: pihlajoki m. Endocrinology. 2012 Jun;153(6):2599-611. doi: 10.1210/en.2011-2135. Epub 2012 Mar 28. Endocrinology. 2012. PMID: 22461617 Free PMC article.
Never underestimate the complexity of remodeling.
Pihlajoki M, Heikinheimo M, Wilson DB. Pihlajoki M, et al. Endocrinology. 2013 Dec;154(12):4446-9. doi: 10.1210/en.2013-1982. Endocrinology. 2013. PMID: 24273232 No abstract available.
Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret.
Schillebeeckx M, Pihlajoki M, Gretzinger E, Yang W, Thol F, Hiller T, Löbs AK, Röhrig T, Schrade A, Cochran R, Jay PY, Heikinheimo M, Mitra RD, Wilson DB. Schillebeeckx M, et al. Among authors: pihlajoki m. Mol Cell Endocrinol. 2015 Jan 5;399:122-30. doi: 10.1016/j.mce.2014.09.029. Epub 2014 Oct 5. Mol Cell Endocrinol. 2015. PMID: 25289806 Free PMC article.
GATA4 is a key regulator of steroidogenesis and glycolysis in mouse Leydig cells.
Schrade A, Kyrönlahti A, Akinrinade O, Pihlajoki M, Häkkinen M, Fischer S, Alastalo TP, Velagapudi V, Toppari J, Wilson DB, Heikinheimo M. Schrade A, et al. Among authors: pihlajoki m. Endocrinology. 2015 May;156(5):1860-72. doi: 10.1210/en.2014-1931. Epub 2015 Feb 10. Endocrinology. 2015. PMID: 25668067 Free PMC article.
Adrenocortical zonation, renewal, and remodeling.
Pihlajoki M, Dörner J, Cochran RS, Heikinheimo M, Wilson DB. Pihlajoki M, et al. Front Endocrinol (Lausanne). 2015 Mar 5;6:27. doi: 10.3389/fendo.2015.00027. eCollection 2015. Front Endocrinol (Lausanne). 2015. PMID: 25798129 Free PMC article. Review.
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