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Cholesterol redistribution triggered by CYP46A1 gene therapy improves major hallmarks of Niemann-Pick type C disease but is not sufficient to halt neurodegeneration.
Nunes MJ, Carvalho AN, Reis J, Costa D, Moutinho M, Mateus J, Mendes de Almeida R, Brito S, Risso D, Nunes S, Castro-Caldas M, Gama MJ, Rodrigues CMP, Xapelli S, Diógenes MJ, Cartier N, Chali F, Piguet F, Rodrigues E. Nunes MJ, et al. Among authors: piguet f. Biochim Biophys Acta Mol Basis Dis. 2024 Mar;1870(3):166993. doi: 10.1016/j.bbadis.2023.166993. Epub 2023 Dec 22. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38142760 Free article.
Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain.
Orefice NS, Souchet B, Braudeau J, Alves S, Piguet F, Collaud F, Ronzitti G, Tada S, Hantraye P, Mingozzi F, Ducongé F, Cartier N. Orefice NS, et al. Among authors: piguet f. Mol Ther Methods Clin Dev. 2019 Jul 3;14:237-251. doi: 10.1016/j.omtm.2019.06.005. eCollection 2019 Sep 13. Mol Ther Methods Clin Dev. 2019. PMID: 31440523 Free PMC article.
Bioelectronic cell-based device provides a strategy for the treatment of the experimental model of multiple sclerosis.
Audouard E, Michel F, Pierroz V, Kim T, Rousselot L, Gillet-Legrand B, Dufayet-Chauffaut G, Buchmann P, Florea M, Khel A, Altynbekova K, Delgaldo C, Escudero E, Soler ABA, Cartier N, Piguet F, Folcher M. Audouard E, et al. Among authors: piguet f. J Control Release. 2022 Dec;352:994-1008. doi: 10.1016/j.jconrel.2022.11.008. Epub 2022 Nov 16. J Control Release. 2022. PMID: 36370877 Free PMC article.
39 results