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Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2.
Pietiäinen V, Polso M, Migh E, Guckelsberger C, Harmati M, Diosdi A, Turunen L, Hassinen A, Potdar S, Koponen A, Sebestyen EG, Kovacs F, Kriston A, Hollandi R, Burian K, Terhes G, Visnyovszki A, Fodor E, Lacza Z, Kantele A, Kolehmainen P, Kakkola L, Strandin T, Levanov L, Kallioniemi O, Kemeny L, Julkunen I, Vapalahti O, Buzas K, Paavolainen L, Horvath P, Hepojoki J. Pietiäinen V, et al. Cell Rep Methods. 2023 Aug 22;3(8):100565. doi: 10.1016/j.crmeth.2023.100565. eCollection 2023 Aug 28. Cell Rep Methods. 2023. PMID: 37671026 Free PMC article.
Loss of DIAPH1 causes SCBMS, combined immunodeficiency, and mitochondrial dysfunction.
Kaustio M, Nayebzadeh N, Hinttala R, Tapiainen T, Åström P, Mamia K, Pernaa N, Lehtonen J, Glumoff V, Rahikkala E, Honkila M, Olsén P, Hassinen A, Polso M, Al Sukaiti N, Al Shekaili J, Al Kindi M, Al Hashmi N, Almusa H, Bulanova D, Haapaniemi E, Chen P, Suo-Palosaari M, Vieira P, Tuominen H, Kokkonen H, Al Macki N, Al Habsi H, Löppönen T, Rantala H, Pietiäinen V, Zhang SY, Renko M, Hautala T, Al Farsi T, Uusimaa J, Saarela J. Kaustio M, et al. Among authors: pietiainen v. J Allergy Clin Immunol. 2021 Aug;148(2):599-611. doi: 10.1016/j.jaci.2020.12.656. Epub 2021 Mar 1. J Allergy Clin Immunol. 2021. PMID: 33662367 Free article. Clinical Trial.
Regression plane concept for analysing continuous cellular processes with machine learning.
Szkalisity A, Piccinini F, Beleon A, Balassa T, Varga IG, Migh E, Molnar C, Paavolainen L, Timonen S, Banerjee I, Ikonen E, Yamauchi Y, Ando I, Peltonen J, Pietiäinen V, Honti V, Horvath P. Szkalisity A, et al. Among authors: pietiainen v. Nat Commun. 2021 May 5;12(1):2532. doi: 10.1038/s41467-021-22866-x. Nat Commun. 2021. PMID: 33953203 Free PMC article.
SARS-CoV-2-host proteome interactions for antiviral drug discovery.
Liu X, Huuskonen S, Laitinen T, Redchuk T, Bogacheva M, Salokas K, Pöhner I, Öhman T, Tonduru AK, Hassinen A, Gawriyski L, Keskitalo S, Vartiainen MK, Pietiäinen V, Poso A, Varjosalo M. Liu X, et al. Among authors: pietiainen v. Mol Syst Biol. 2021 Nov;17(11):e10396. doi: 10.15252/msb.202110396. Mol Syst Biol. 2021. PMID: 34709727 Free PMC article.
iTReX: Interactive exploration of mono- and combination therapy dose response profiling data.
ElHarouni D, Berker Y, Peterziel H, Gopisetty A, Turunen L, Kreth S, Stainczyk SA, Oehme I, Pietiäinen V, Jäger N, Witt O, Schlesner M, Oppermann S. ElHarouni D, et al. Among authors: pietiainen v. Pharmacol Res. 2022 Jan;175:105996. doi: 10.1016/j.phrs.2021.105996. Epub 2021 Nov 27. Pharmacol Res. 2022. PMID: 34848323 Free article.
29 results