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Senolytics reduce coronavirus-related mortality in old mice.
Camell CD, Yousefzadeh MJ, Zhu Y, Prata LGPL, Huggins MA, Pierson M, Zhang L, O'Kelly RD, Pirtskhalava T, Xun P, Ejima K, Xue A, Tripathi U, Espindola-Netto JM, Giorgadze N, Atkinson EJ, Inman CL, Johnson KO, Cholensky SH, Carlson TW, LeBrasseur NK, Khosla S, O'Sullivan MG, Allison DB, Jameson SC, Meves A, Li M, Prakash YS, Chiarella SE, Hamilton SE, Tchkonia T, Niedernhofer LJ, Kirkland JL, Robbins PD. Camell CD, et al. Among authors: pierson m. Science. 2021 Jul 16;373(6552):eabe4832. doi: 10.1126/science.abe4832. Epub 2021 Jun 8. Science. 2021. PMID: 34103349 Free PMC article.
Microbial Exposure Enhances Immunity to Pathogens Recognized by TLR2 but Increases Susceptibility to Cytokine Storm through TLR4 Sensitization.
Huggins MA, Sjaastad FV, Pierson M, Kucaba TA, Swanson W, Staley C, Weingarden AR, Jensen IJ, Danahy DB, Badovinac VP, Jameson SC, Vezys V, Masopust D, Khoruts A, Griffith TS, Hamilton SE. Huggins MA, et al. Among authors: pierson m. Cell Rep. 2019 Aug 13;28(7):1729-1743.e5. doi: 10.1016/j.celrep.2019.07.028. Cell Rep. 2019. PMID: 31412243 Free PMC article.
New Insights into the Immune System Using Dirty Mice.
Hamilton SE, Badovinac VP, Beura LK, Pierson M, Jameson SC, Masopust D, Griffith TS. Hamilton SE, et al. Among authors: pierson m. J Immunol. 2020 Jul 1;205(1):3-11. doi: 10.4049/jimmunol.2000171. J Immunol. 2020. PMID: 32571979 Free PMC article. Review.
Mice with diverse microbial exposure histories as a model for preclinical vaccine testing.
Fiege JK, Block KE, Pierson MJ, Nanda H, Shepherd FK, Mickelson CK, Stolley JM, Matchett WE, Wijeyesinghe S, Meyerholz DK, Vezys V, Shen SS, Hamilton SE, Masopust D, Langlois RA. Fiege JK, et al. Cell Host Microbe. 2021 Dec 8;29(12):1815-1827.e6. doi: 10.1016/j.chom.2021.10.001. Epub 2021 Nov 2. Cell Host Microbe. 2021. PMID: 34731647 Free PMC article.
510 results