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Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks.
Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY, Ciccolallo L, Craig PS, De Vries RBM, Dorne JLCM, Druwe IL, Edwards SW, Eskes C, Georgiadis M, Hartung T, Kienzler A, Kristjansson EA, Lam J, Martino L, Meek B, Morgan RL, Munoz-Guajardo I, Noyes PD, Parmelli E, Piersma A, Rooney A, Sena E, Sullivan K, Tarazona J, Terron A, Thayer K, Turner J, Verbeek J, Verloo D, Vinken M, Watford S, Whaley P, Wikoff D, Willett K, Tsaioun K. Hoffmann S, et al. Among authors: piersma a. ALTEX. 2022;39(3):499–518. doi: 10.14573/altex.2202141. Epub 2022 Mar 1. ALTEX. 2022. PMID: 35258090 Free PMC article.
Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
Aschner M, Ceccatelli S, Daneshian M, Fritsche E, Hasiwa N, Hartung T, Hogberg HT, Leist M, Li A, Mundi WR, Padilla S, Piersma AH, Bal-Price A, Seiler A, Westerink RH, Zimmer B, Lein PJ. Aschner M, et al. Among authors: piersma ah. ALTEX. 2017;34(1):49-74. doi: 10.14573/altex.1604201. Epub 2016 Jul 25. ALTEX. 2017. PMID: 27452664 Free PMC article.
Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.
Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M. Bal-Price A, et al. Among authors: piersma ah. ALTEX. 2018;35(3):306-352. doi: 10.14573/altex.1712081. Epub 2018 Feb 23. ALTEX. 2018. PMID: 29485663 Free PMC article.
Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies.
Piersma AH, Burgdorf T, Louekari K, Desprez B, Taalman R, Landsiedel R, Barroso J, Rogiers V, Eskes C, Oelgeschläger M, Whelan M, Braeuning A, Vinggaard AM, Kienhuis A, van Benthem J, Ezendam J. Piersma AH, et al. Toxicol In Vitro. 2018 Aug;50:62-74. doi: 10.1016/j.tiv.2018.02.018. Epub 2018 Mar 2. Toxicol In Vitro. 2018. PMID: 29501630 Free article.
Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology - Evolution versus revolution.
Burgdorf T, Piersma AH, Landsiedel R, Clewell R, Kleinstreuer N, Oelgeschläger M, Desprez B, Kienhuis A, Bos P, de Vries R, de Wit L, Seidle T, Scheel J, Schönfelder G, van Benthem J, Vinggaard AM, Eskes C, Ezendam J. Burgdorf T, et al. Among authors: piersma ah. Toxicol In Vitro. 2019 Sep;59:1-11. doi: 10.1016/j.tiv.2019.03.039. Epub 2019 Apr 1. Toxicol In Vitro. 2019. PMID: 30946968
A mode-of-action ontology model for safety evaluation of chemicals: Outcome of a series of workshops on repeated dose toxicity.
Desprez B, Birk B, Blaauboer B, Boobis A, Carmichael P, Cronin MTD, Curie R, Daston G, Hubesch B, Jennings P, Klaric M, Kroese D, Mahony C, Ouédraogo G, Piersma A, Richarz AN, Schwarz M, van Benthem J, van de Water B, Vinken M. Desprez B, et al. Among authors: piersma a. Toxicol In Vitro. 2019 Sep;59:44-50. doi: 10.1016/j.tiv.2019.04.005. Epub 2019 Apr 4. Toxicol In Vitro. 2019. PMID: 30954655
Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity.
Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M. Bal-Price A, et al. Among authors: piersma ah. ALTEX. 2019;36(3):506. doi: 10.14573/altex.1904112. ALTEX. 2019. PMID: 31329255 Free article.
Safer chemicals using less animals: kick-off of the European ONTOX project.
Vinken M, Benfenati E, Busquet F, Castell J, Clevert DA, de Kok TM, Dirven H, Fritsche E, Geris L, Gozalbes R, Hartung T, Jennen D, Jover R, Kandarova H, Kramer N, Krul C, Luechtefeld T, Masereeuw R, Roggen E, Schaller S, Vanhaecke T, Yang C, Piersma AH. Vinken M, et al. Toxicology. 2021 Jun 30;458:152846. doi: 10.1016/j.tox.2021.152846. Epub 2021 Jun 30. Toxicology. 2021. PMID: 34216698 Free article. Review.
243 results