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A Novel Mitochondria-Targeting Iron Chelator Neuroprotects Multimodally via HIF-1 Modulation Against a Mitochondrial Toxin in a Dopaminergic Cell Model of Parkinson's Disease.
Fouché B, Turner S, Gorham R, Stephenson EJ, Gutbier S, Elson JL, García-Beltrán O, Van Der Westhuizen FH, Pienaar IS. Fouché B, et al. Among authors: pienaar is. Mol Neurobiol. 2023 Feb;60(2):749-767. doi: 10.1007/s12035-022-03107-8. Epub 2022 Nov 11. Mol Neurobiol. 2023. PMID: 36357615
Synthesis, physicochemical characterization and neuroprotective evaluation of novel 1-hydroxypyrazin-2(1H)-one iron chelators in an in vitro cell model of Parkinson's disease.
Lewis FW, Bird K, Navarro JP, El Fallah R, Brandel J, Hubscher-Bruder V, Tsatsanis A, Duce JA, Tétard D, Bourne S, Maina M, Pienaar IS. Lewis FW, et al. Among authors: pienaar is. Dalton Trans. 2022 Mar 1;51(9):3590-3603. doi: 10.1039/d1dt02604f. Dalton Trans. 2022. PMID: 35147617 Free PMC article.
Dissociable contributions of mediodorsal and anterior thalamic nuclei in visual attentional performance: A comparison using nicotinic and muscarinic cholinergic receptor antagonists.
Mantanona CP, Božič T, Chudasama Y, Robbins TW, Dalley JW, Alsiö J, Pienaar IS. Mantanona CP, et al. Among authors: pienaar is. J Psychopharmacol. 2020 Dec;34(12):1371-1381. doi: 10.1177/0269881120965880. Epub 2020 Oct 24. J Psychopharmacol. 2020. PMID: 33103560 Free PMC article.
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants.
Gutbier S, Kyriakou S, Schildknecht S, Ückert AK, Brüll M, Lewis F, Dickens D, Pearson L, Elson JL, Michel S, Hubscher-Bruder V, Brandel J, Tetard D, Leist M, Pienaar IS. Gutbier S, et al. Among authors: pienaar is. Arch Toxicol. 2020 Sep;94(9):3105-3123. doi: 10.1007/s00204-020-02826-y. Epub 2020 Jun 30. Arch Toxicol. 2020. PMID: 32607613 Free PMC article.
45 results