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Role of conserved cysteines in the alphavirus E3 protein.
Parrott MM, Sitarski SA, Arnold RJ, Picton LK, Hill RB, Mukhopadhyay S. Parrott MM, et al. Among authors: picton lk. J Virol. 2009 Mar;83(6):2584-91. doi: 10.1128/JVI.02158-08. Epub 2008 Dec 24. J Virol. 2009. PMID: 19109378 Free PMC article.
Immune receptor inhibition through enforced phosphatase recruitment.
Fernandes RA, Su L, Nishiga Y, Ren J, Bhuiyan AM, Cheng N, Kuo CJ, Picton LK, Ohtsuki S, Majzner RG, Rietberg SP, Mackall CL, Yin Q, Ali LR, Yang X, Savvides CS, Sage J, Dougan M, Garcia KC. Fernandes RA, et al. Among authors: picton lk. Nature. 2020 Oct;586(7831):779-784. doi: 10.1038/s41586-020-2851-2. Epub 2020 Oct 21. Nature. 2020. PMID: 33087934 Free PMC article.
Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance.
Hirai T, Ramos TL, Lin PY, Simonetta F, Su LL, Picton LK, Baker J, Lin JX, Li P, Seo K, Lohmeyer JK, Bolivar-Wagers S, Mavers M, Leonard WJ, Blazar BR, Garcia KC, Negrin RS. Hirai T, et al. Among authors: picton lk. J Clin Invest. 2021 Apr 15;131(8):e139991. doi: 10.1172/JCI139991. J Clin Invest. 2021. PMID: 33855972 Free PMC article.
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.
Glassman CR, Su L, Majri-Morrison SS, Winkelmann H, Mo F, Li P, Pérez-Cruz M, Ho PP, Koliesnik I, Nagy N, Hnizdilova T, Picton LK, Kovar M, Bollyky P, Steinman L, Meyer E, Piehler J, Leonard WJ, Garcia KC. Glassman CR, et al. Among authors: picton lk. Elife. 2021 May 18;10:e65777. doi: 10.7554/eLife.65777. Elife. 2021. PMID: 34003116 Free PMC article.
An engineered IL-2 partial agonist promotes CD8+ T cell stemness.
Mo F, Yu Z, Li P, Oh J, Spolski R, Zhao L, Glassman CR, Yamamoto TN, Chen Y, Golebiowski FM, Hermans D, Majri-Morrison S, Picton LK, Liao W, Ren M, Zhuang X, Mitra S, Lin JX, Gattinoni L, Powell JD, Restifo NP, Garcia KC, Leonard WJ. Mo F, et al. Among authors: picton lk. Nature. 2021 Sep;597(7877):544-548. doi: 10.1038/s41586-021-03861-0. Epub 2021 Sep 15. Nature. 2021. PMID: 34526724 Free PMC article.
26 results