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Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions.
Sollier J, Basler M, Broz P, Dittrich PS, Drescher K, Egli A, Harms A, Hierlemann A, Hiller S, King CG, McKinney JD, Moran-Gilad J, Neher RA, Page MGP, Panke S, Persat A, Picotti P, Rentsch KM, Rivera-Fuentes P, Sauer U, Stolz D, Tschudin-Sutter S, van Delden C, van Nimwegen E, Veening JW, Zampieri M, Zinkernagel AS, Khanna N, Bumann D, Jenal U, Dehio C. Sollier J, et al. Among authors: picotti p. Nat Microbiol. 2024 Jan;9(1):1-3. doi: 10.1038/s41564-023-01566-w. Nat Microbiol. 2024. PMID: 38177300 No abstract available.
Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity.
Paukštytė J, López Cabezas RM, Feng Y, Tong K, Schnyder D, Elomaa E, Gregorova P, Doudin M, Särkkä M, Sarameri J, Lippi A, Vihinen H, Juutila J, Nieminen A, Törönen P, Holm L, Jokitalo E, Krisko A, Huiskonen J, Sarin LP, Hietakangas V, Picotti P, Barral Y, Saarikangas J. Paukštytė J, et al. Among authors: picotti p. Mol Cell. 2023 Sep 21;83(18):3360-3376.e11. doi: 10.1016/j.molcel.2023.08.015. Epub 2023 Sep 11. Mol Cell. 2023. PMID: 37699397 Free article.
Systematic identification of structure-specific protein-protein interactions.
Holfeld A, Schuster D, Sesterhenn F, Gillingham AK, Stalder P, Haenseler W, Barrio-Hernandez I, Ghosh D, Vowles J, Cowley SA, Nagel L, Khanppnavar B, Serdiuk T, Beltrao P, Korkhov VM, Munro S, Riek R, de Souza N, Picotti P. Holfeld A, et al. Among authors: picotti p. Mol Syst Biol. 2024 May 3. doi: 10.1038/s44320-024-00037-6. Online ahead of print. Mol Syst Biol. 2024. PMID: 38702390
In situ analysis of osmolyte mechanisms of proteome thermal stabilization.
Pepelnjak M, Velten B, Näpflin N, von Rosen T, Palmiero UC, Ko JH, Maynard HD, Arosio P, Weber-Ban E, de Souza N, Huber W, Picotti P. Pepelnjak M, et al. Among authors: picotti p. Nat Chem Biol. 2024 Feb 29. doi: 10.1038/s41589-024-01568-7. Online ahead of print. Nat Chem Biol. 2024. PMID: 38424171
Systematic identification of 20S proteasome substrates.
Pepelnjak M, Rogawski R, Arkind G, Leushkin Y, Fainer I, Ben-Nissan G, Picotti P, Sharon M. Pepelnjak M, et al. Among authors: picotti p. Mol Syst Biol. 2024 Apr;20(4):403-427. doi: 10.1038/s44320-024-00015-y. Epub 2024 Jan 29. Mol Syst Biol. 2024. PMID: 38287148 Free PMC article.
Structure of the connexin-43 gap junction channel in a putative closed state.
Qi C, Acosta Gutierrez S, Lavriha P, Othman A, Lopez-Pigozzi D, Bayraktar E, Schuster D, Picotti P, Zamboni N, Bortolozzi M, Gervasio FL, Korkhov VM. Qi C, et al. Among authors: picotti p. Elife. 2023 Aug 3;12:RP87616. doi: 10.7554/eLife.87616. Elife. 2023. PMID: 37535063 Free PMC article.
Genetic effects on molecular network states explain complex traits.
Weith M, Großbach J, Clement-Ziza M, Gillet L, Rodríguez-López M, Marguerat S, Workman CT, Picotti P, Bähler J, Aebersold R, Beyer A. Weith M, et al. Among authors: picotti p. Mol Syst Biol. 2023 Aug 8;19(8):e11493. doi: 10.15252/msb.202211493. Epub 2023 Jul 24. Mol Syst Biol. 2023. PMID: 37485750 Free PMC article.
116 results