Pickles RJ - Search Results

1

Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein.

Shi Y, Zeida A, Edwards CE, Mallory ML, Sastre S, Machado MR, Pickles RJ, Fu L, Liu K, Yang J, Baric RS, Boucher RC, Radi R, Carroll KS. Shi Y, et al. Among authors: pickles rj. Proc Natl Acad Sci U S A. 2022 Feb 8;119(6):e2120419119. doi: 10.1073/pnas.2120419119. Proc Natl Acad Sci U S A. 2022. PMID: 35074895 Free PMC article.

2

Gene therapy for cystic fibrosis using E1-deleted adenovirus: a phase I trial in the nasal cavity. The University of North Carolina at Chapel Hill.

Boucher RC, Knowles MR, Johnson LG, Olsen JC, Pickles R, Wilson JM, Engelhardt J, Yang Y, Grossman M. Boucher RC, et al. Hum Gene Ther. 1994 May;5(5):615-39. doi: 10.1089/hum.1994.5.5-615. Hum Gene Ther. 1994. PMID: 7519885 Clinical Trial.

3

Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans.

Grubb BR, Pickles RJ, Ye H, Yankaskas JR, Vick RN, Engelhardt JF, Wilson JM, Johnson LG, Boucher RC. Grubb BR, et al. Among authors: pickles rj. Nature. 1994 Oct 27;371(6500):802-6. doi: 10.1038/371802a0. Nature. 1994. PMID: 7523956

4

Efficient adenovirus-mediated gene transfer to basal but not columnar cells of cartilaginous airway epithelia.

Pickles RJ, Barker PM, Ye H, Boucher RC. Pickles RJ, et al. Hum Gene Ther. 1996 May 20;7(8):921-31. doi: 10.1089/hum.1996.7.8-921. Hum Gene Ther. 1996. PMID: 8727506

5

In vitro assessment of variables affecting the efficiency and efficacy of adenovirus-mediated gene transfer to cystic fibrosis airway epithelia.

Johnson LG, Pickles RJ, Boyles SE, Morris JC, Ye H, Zhou Z, Olsen JC, Boucher RC. Johnson LG, et al. Among authors: pickles rj. Hum Gene Ther. 1996 Jan;7(1):51-9. doi: 10.1089/hum.1996.7.1-51. Hum Gene Ther. 1996. PMID: 8825868

6

Transduction of non-small cell lung cancer cells by adenoviral and retroviral vectors.

Batra RK, Olsen JC, Pickles RJ, Hoganson DK, Boucher RC. Batra RK, et al. Among authors: pickles rj. Am J Respir Cell Mol Biol. 1998 Mar;18(3):402-10. doi: 10.1165/ajrcmb.18.3.2784. Am J Respir Cell Mol Biol. 1998. PMID: 9490658

7

Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer.

Pickles RJ, McCarty D, Matsui H, Hart PJ, Randell SH, Boucher RC. Pickles RJ, et al. J Virol. 1998 Jul;72(7):6014-23. doi: 10.1128/JVI.72.7.6014-6023.1998. J Virol. 1998. PMID: 9621064 Free PMC article.

8

G-protein-coupled receptors as targets for gene transfer vectors using natural small-molecule ligands.

Kreda SM, Pickles RJ, Lazarowski ER, Boucher RC. Kreda SM, et al. Among authors: pickles rj. Nat Biotechnol. 2000 Jun;18(6):635-40. doi: 10.1038/76479. Nat Biotechnol. 2000. PMID: 10835601

9

Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer.

Pickles RJ, Fahrner JA, Petrella JM, Boucher RC, Bergelson JM. Pickles RJ, et al. J Virol. 2000 Jul;74(13):6050-7. doi: 10.1128/jvi.74.13.6050-6057.2000. J Virol. 2000. PMID: 10846088 Free PMC article.

10

Respiratory syncytial virus infection of human airway epithelial cells is polarized, specific to ciliated cells, and without obvious cytopathology.

Zhang L, Peeples ME, Boucher RC, Collins PL, Pickles RJ. Zhang L, et al. Among authors: pickles rj. J Virol. 2002 Jun;76(11):5654-66. doi: 10.1128/jvi.76.11.5654-5666.2002. J Virol. 2002. PMID: 11991994 Free PMC article.

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