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DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts.
Richards LA, Kumari A, Knezevic K, Thoms JA, von Jonquieres G, Napier CE, Ali Z, O'Brien R, Marks-Bluth J, Maritz MF, Pickett HA, Morris J, Pimanda JE, MacKenzie KL. Richards LA, et al. Among authors: pickett ha. Haematologica. 2020 Jun;105(6):1517-1526. doi: 10.3324/haematol.2018.215699. Epub 2019 Aug 14. Haematologica. 2020. PMID: 31413099 Free PMC article.
qmotif: determination of telomere content from whole-genome sequence data.
Holmes O, Nones K, Tang YH, Loffler KA, Lee M, Patch AM, Dagg RA, Lau LMS, Leonard C, Wood S, Xu Q, Pickett HA, Reddel RR, Barbour AP, Grimmond SM, Waddell N, Pearson JV. Holmes O, et al. Among authors: pickett ha. Bioinform Adv. 2022 Jan 31;2(1):vbac005. doi: 10.1093/bioadv/vbac005. eCollection 2022. Bioinform Adv. 2022. PMID: 36699384 Free PMC article.
MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.
O'Brien R, Tran SL, Maritz MF, Liu B, Kong CF, Purgato S, Yang C, Murray J, Russell AJ, Flemming CL, von Jonquieres G, Pickett HA, London WB, Haber M, Gunaratne PH, Norris MD, Perini G, Fletcher JI, MacKenzie KL. O'Brien R, et al. Among authors: pickett ha. Cancer Res. 2016 Jun 15;76(12):3604-17. doi: 10.1158/0008-5472.CAN-15-0879. Epub 2016 Apr 13. Cancer Res. 2016. PMID: 27197171
Extensive Proliferation of Human Cancer Cells with Ever-Shorter Telomeres.
Dagg RA, Pickett HA, Neumann AA, Napier CE, Henson JD, Teber ET, Arthur JW, Reynolds CP, Murray J, Haber M, Sobinoff AP, Lau LMS, Reddel RR. Dagg RA, et al. Among authors: pickett ha. Cell Rep. 2017 Jun 20;19(12):2544-2556. doi: 10.1016/j.celrep.2017.05.087. Cell Rep. 2017. PMID: 28636942 Free article.
Telomere sequence content can be used to determine ALT activity in tumours.
Lee M, Teber ET, Holmes O, Nones K, Patch AM, Dagg RA, Lau LMS, Lee JH, Napier CE, Arthur JW, Grimmond SM, Hayward NK, Johansson PA, Mann GJ, Scolyer RA, Wilmott JS, Reddel RR, Pearson JV, Waddell N, Pickett HA. Lee M, et al. Among authors: pickett ha. Nucleic Acids Res. 2018 Jun 1;46(10):4903-4918. doi: 10.1093/nar/gky297. Nucleic Acids Res. 2018. PMID: 29718321 Free PMC article.
Telomerase promotes formation of a telomere protective complex in cancer cells.
Perera ON, Sobinoff AP, Teber ET, Harman A, Maritz MF, Yang SF, Pickett HA, Cesare AJ, Arthur JW, MacKenzie KL, Bryan TM. Perera ON, et al. Among authors: pickett ha. Sci Adv. 2019 Oct 2;5(10):eaav4409. doi: 10.1126/sciadv.aav4409. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31616780 Free PMC article.
Targeted Therapy of TERT-Rearranged Neuroblastoma with BET Bromodomain Inhibitor and Proteasome Inhibitor Combination Therapy.
Chen J, Nelson C, Wong M, Tee AE, Liu PY, La T, Fletcher JI, Kamili A, Mayoh C, Bartenhagen C, Trahair TN, Xu N, Jayatilleke N, Wong M, Peng H, Atmadibrata B, Cheung BB, Lan Q, Bryan TM, Mestdagh P, Vandesompele J, Combaret V, Boeva V, Wang JY, Janoueix-Lerosey I, Cowley MJ, MacKenzie KL, Dolnikov A, Li J, Polly P, Marshall GM, Reddel RR, Norris MD, Haber M, Fischer M, Zhang XD, Pickett HA, Liu T. Chen J, et al. Among authors: pickett ha. Clin Cancer Res. 2021 Mar 1;27(5):1438-1451. doi: 10.1158/1078-0432.CCR-20-3044. Epub 2020 Dec 11. Clin Cancer Res. 2021. PMID: 33310889
121 results