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Brd4 is required for chondrocyte differentiation and endochondral ossification.
Paradise CR, Galvan ML, Pichurin O, Jerez S, Kubrova E, Dehghani SS, Carrasco ME, Thaler R, Larson AN, van Wijnen AJ, Dudakovic A. Paradise CR, et al. Among authors: pichurin o. Bone. 2022 Jan;154:116234. doi: 10.1016/j.bone.2021.116234. Epub 2021 Oct 23. Bone. 2022. PMID: 34700039 Free PMC article.
MicroRNA-101a enhances trabecular bone accrual in male mice.
Dudakovic A, Jerez S, Deosthale PJ, Denbeigh JM, Paradise CR, Gluscevic M, Zan P, Begun DL, Camilleri ET, Pichurin O, Khani F, Thaler R, Lian JB, Stein GS, Westendorf JJ, Plotkin LI, van Wijnen AJ. Dudakovic A, et al. Among authors: pichurin o. Sci Rep. 2022 Aug 3;12(1):13361. doi: 10.1038/s41598-022-17579-0. Sci Rep. 2022. PMID: 35922466 Free PMC article.
Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice.
Dudakovic A, Camilleri ET, Paradise CR, Samsonraj RM, Gluscevic M, Paggi CA, Begun DL, Khani F, Pichurin O, Ahmed FS, Elsayed R, Elsalanty M, McGee-Lawrence ME, Karperien M, Riester SM, Thaler R, Westendorf JJ, van Wijnen AJ. Dudakovic A, et al. Among authors: pichurin o. J Biol Chem. 2018 Aug 17;293(33):12894-12907. doi: 10.1074/jbc.RA118.002983. Epub 2018 Jun 13. J Biol Chem. 2018. PMID: 29899112 Free PMC article.
Inhibition of the epigenetic suppressor EZH2 primes osteogenic differentiation mediated by BMP2.
Dudakovic A, Samsonraj RM, Paradise CR, Galeano-Garces C, Mol MO, Galeano-Garces D, Zan P, Galvan ML, Hevesi M, Pichurin O, Thaler R, Begun DL, Kloen P, Karperien M, Larson AN, Westendorf JJ, Cool SM, van Wijnen AJ. Dudakovic A, et al. Among authors: pichurin o. J Biol Chem. 2020 Jun 5;295(23):7877-7893. doi: 10.1074/jbc.RA119.011685. Epub 2020 Apr 24. J Biol Chem. 2020. PMID: 32332097 Free PMC article.
Vitamin C epigenetically controls osteogenesis and bone mineralization.
Thaler R, Khani F, Sturmlechner I, Dehghani SS, Denbeigh JM, Zhou X, Pichurin O, Dudakovic A, Jerez SS, Zhong J, Lee JH, Natarajan R, Kalajzic I, Jiang YH, Deyle DR, Paschalis EP, Misof BM, Ordog T, van Wijnen AJ. Thaler R, et al. Among authors: pichurin o. Nat Commun. 2022 Oct 6;13(1):5883. doi: 10.1038/s41467-022-32915-8. Nat Commun. 2022. PMID: 36202795 Free PMC article.
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