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Human NLRP1 is a sensor for double-stranded RNA.
Bauernfried S, Scherr MJ, Pichlmair A, Duderstadt KE, Hornung V. Bauernfried S, et al. Among authors: pichlmair a. Science. 2021 Jan 29;371(6528):eabd0811. doi: 10.1126/science.abd0811. Epub 2020 Nov 26. Science. 2021. PMID: 33243852
Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
Lampl S, Janas MK, Donakonda S, Brugger M, Lohr K, Schneider A, Manske K, Sperl LE, Kläger S, Küster B, Wettmarshausen J, Müller C, Laschinger M, Hartmann D, Hüser N, Perocchi F, Schmitt-Kopplin P, Hagn F, Zender L, Hornung V, Borner C, Pichlmair A, Kashkar H, Klingenspor M, Prinz M, Schreiner S, Conrad M, Jost PJ, Zischka H, Steiger K, Krönke M, Zehn D, Protzer U, Heikenwälder M, Knolle PA, Wohlleber D. Lampl S, et al. Among authors: pichlmair a. J Hepatol. 2020 Dec;73(6):1347-1359. doi: 10.1016/j.jhep.2020.06.026. Epub 2020 Jun 26. J Hepatol. 2020. PMID: 32598967
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication.
Tsukamoto Y, Hiono T, Yamada S, Matsuno K, Faist A, Claff T, Hou J, Namasivayam V, Vom Hemdt A, Sugimoto S, Ng JY, Christensen MH, Tesfamariam YM, Wolter S, Juranek S, Zillinger T, Bauer S, Hirokawa T, Schmidt FI, Kochs G, Shimojima M, Huang YS, Pichlmair A, Kümmerer BM, Sakoda Y, Schlee M, Brunotte L, Müller CE, Igarashi M, Kato H. Tsukamoto Y, et al. Among authors: pichlmair a. Science. 2023 Feb 10;379(6632):586-591. doi: 10.1126/science.add0875. Epub 2023 Feb 9. Science. 2023. PMID: 36758070
Cytoplasmic sensing of viral nucleic acids.
Habjan M, Pichlmair A. Habjan M, et al. Among authors: pichlmair a. Curr Opin Virol. 2015 Apr;11:31-7. doi: 10.1016/j.coviro.2015.01.012. Epub 2015 Feb 7. Curr Opin Virol. 2015. PMID: 25668758 Free PMC article. Review.
A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle.
Płaszczyca A, Scaturro P, Neufeldt CJ, Cortese M, Cerikan B, Ferla S, Brancale A, Pichlmair A, Bartenschlager R. Płaszczyca A, et al. Among authors: pichlmair a. PLoS Pathog. 2019 May 9;15(5):e1007736. doi: 10.1371/journal.ppat.1007736. eCollection 2019 May. PLoS Pathog. 2019. PMID: 31071189 Free PMC article.
90 results