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Integrating in vitro and in silico approaches to evaluate the "dual functionality" of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils.
Haj E, Losev Y, Guru KrishnaKumar V, Pichinuk E, Engel H, Raveh A, Gazit E, Segal D. Haj E, et al. Among authors: pichinuk e. Biochim Biophys Acta Gen Subj. 2018 Jul;1862(7):1565-1575. doi: 10.1016/j.bbagen.2018.04.001. Epub 2018 Apr 7. Biochim Biophys Acta Gen Subj. 2018. PMID: 29634991
Purpurin modulates Tau-derived VQIVYK fibrillization and ameliorates Alzheimer's disease-like symptoms in animal model.
Viswanathan GK, Shwartz D, Losev Y, Arad E, Shemesh C, Pichinuk E, Engel H, Raveh A, Jelinek R, Cooper I, Gosselet F, Gazit E, Segal D. Viswanathan GK, et al. Among authors: pichinuk e. Cell Mol Life Sci. 2020 Jul;77(14):2795-2813. doi: 10.1007/s00018-019-03312-0. Epub 2019 Sep 27. Cell Mol Life Sci. 2020. PMID: 31562564 Free PMC article.
Antibody targeting of cell-bound MUC1 SEA domain kills tumor cells.
Pichinuk E, Benhar I, Jacobi O, Chalik M, Weiss L, Ziv R, Sympson C, Karwa A, Smorodinsky NI, Rubinstein DB, Wreschner DH. Pichinuk E, et al. Cancer Res. 2012 Jul 1;72(13):3324-36. doi: 10.1158/0008-5472.CAN-12-0067. Epub 2012 Apr 16. Cancer Res. 2012. PMID: 22507854
MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA.
Chalick M, Jacobi O, Pichinuk E, Garbar C, Bensussan A, Meeker A, Ziv R, Zehavi T, Smorodinsky NI, Hilkens J, Hanisch FG, Rubinstein DB, Wreschner DH. Chalick M, et al. Among authors: pichinuk e. PLoS One. 2016 Oct 21;11(10):e0165031. doi: 10.1371/journal.pone.0165031. eCollection 2016. PLoS One. 2016. PMID: 27768738 Free PMC article.
PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.
Levitin F, Weiss M, Hahn Y, Stern O, Papke RL, Matusik R, Nandana SR, Ziv R, Pichinuk E, Salame S, Bera T, Vincent J, Lee B, Pastan I, Wreschner DH. Levitin F, et al. Among authors: pichinuk e. J Biol Chem. 2008 Jun 13;283(24):16928-39. doi: 10.1074/jbc.M801454200. Epub 2008 Apr 3. J Biol Chem. 2008. PMID: 18387948 Free PMC article.
21 results