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tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa.
Krueger J, Preusse M, Oswaldo Gomez N, Frommeyer YN, Doberenz S, Lorenz A, Kordes A, Grobe S, Müsken M, Depledge DP, Svensson SL, Weiss S, Kaever V, Pich A, Sharma CM, Ignatova Z, Häussler S. Krueger J, et al. Among authors: pich a. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2312874121. doi: 10.1073/pnas.2312874121. Epub 2024 Mar 7. Proc Natl Acad Sci U S A. 2024. PMID: 38451943 Free PMC article.
Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.
Borgert SR, Henke S, Witzgall F, Schmelz S, Zur Lage S, Hotop SK, Stephen S, Lübken D, Krüger J, Gomez NO, van Ham M, Jänsch L, Kalesse M, Pich A, Brönstrup M, Häussler S, Blankenfeldt W. Borgert SR, et al. Among authors: pich a. Nat Commun. 2022 Dec 1;13(1):7402. doi: 10.1038/s41467-022-35030-w. Nat Commun. 2022. PMID: 36456567 Free PMC article.
Pharmacological inhibition of bromodomain and extra-terminal proteins induces an NRF-2-mediated antiviral state that is subverted by SARS-CoV-2 infection.
Mhlekude B, Postmus D, Stenzel S, Weiner J 3rd, Jansen J, Zapatero-Belinchón FJ, Olmer R, Richter A, Heinze J, Heinemann N, Mühlemann B, Schroeder S, Jones TC, Müller MA, Drosten C, Pich A, Thiel V, Martin U, Niemeyer D, Gerold G, Beule D, Goffinet C. Mhlekude B, et al. Among authors: pich a. PLoS Pathog. 2023 Sep 25;19(9):e1011657. doi: 10.1371/journal.ppat.1011657. eCollection 2023 Sep. PLoS Pathog. 2023. PMID: 37747932 Free PMC article.
Obesity impacts hypoxia adaptation of the lung.
Pankoke S, Schweitzer T, Bikker R, Pich A, Pfarrer C, Mühlfeld C, Schipke J. Pankoke S, et al. Among authors: pich a. Am J Physiol Lung Cell Mol Physiol. 2023 Sep 1;325(3):L352-L359. doi: 10.1152/ajplung.00125.2023. Epub 2023 Jul 18. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37461840
Circular RNA circZFPM2 regulates cardiomyocyte hypertrophy and survival.
Neufeldt D, Schmidt A, Mohr E, Lu D, Chatterjee S, Fuchs M, Xiao K, Pan W, Cushman S, Jahn C, Juchem M, Hunkler HJ, Cipriano G, Jürgens B, Schmidt K, Groß S, Jung M, Hoepfner J, Weber N, Foo R, Pich A, Zweigerdt R, Kraft T, Thum T, Bär C. Neufeldt D, et al. Among authors: pich a. Basic Res Cardiol. 2024 Apr 19. doi: 10.1007/s00395-024-01048-y. Online ahead of print. Basic Res Cardiol. 2024. PMID: 38639887
Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo.
Abbas N, Haas JA, Xiao K, Fuchs M, Just A, Pich A, Perbellini F, Werlein C, Ius F, Ruhparwar A, Fiedler J, Weber N, Thum T. Abbas N, et al. Among authors: pich a. Eur Heart J. 2024 Mar 5:ehae102. doi: 10.1093/eurheartj/ehae102. Online ahead of print. Eur Heart J. 2024. PMID: 38442291 No abstract available.
397 results