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Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders.
Wilk CM, Cathomas F, Török O, Le Berichel J, Park MD, Bigenwald C, Heaton GR, Hamon P, Troncoso L, Scull BP, Dangoor D, Silvin A, Fleischmann R, Belabed M, Lin H, Merad Taouli E, Boettcher S, Li L, Aubry A, Manz MG, Kofler JK, Yue Z, Lira SA, Ginhoux F, Crary JF, McClain KL, Picarsic JL, Russo SJ, Allen CE, Merad M. Wilk CM, et al. Among authors: picarsic jl. Immunity. 2023 Dec 12;56(12):2790-2802.e6. doi: 10.1016/j.immuni.2023.11.011. Immunity. 2023. PMID: 38091952
Circulating senescent myeloid cells drive blood brain barrier breakdown and neurodegeneration.
Wilk CM, Cathomas F, Török O, Le Berichel J, Park MD, Heaton GR, Hamon P, Troncoso L, Scull BP, Dangoor D, Silvin A, Fleischmann R, Belabed M, Lin H, Taouli EM, Boettcher S, Manz MG, Kofler JK, Yue Z, Lira SA, Ginhoux F, Crary JF, McClain KL, Picarsic JL, Russo SJ, Allen CE, Merad M. Wilk CM, et al. Among authors: picarsic jl. bioRxiv [Preprint]. 2023 Oct 11:2023.10.10.561744. doi: 10.1101/2023.10.10.561744. bioRxiv. 2023. PMID: 37873371 Free PMC article. Updated. Preprint.
International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults.
Goyal G, Tazi A, Go RS, Rech KL, Picarsic JL, Vassallo R, Young JR, Cox CW, Van Laar J, Hermiston ML, Cao XX, Makras P, Kaltsas G, Haroche J, Collin M, McClain KL, Diamond EL, Girschikofsky M. Goyal G, et al. Among authors: picarsic jl. Blood. 2022 Apr 28;139(17):2601-2621. doi: 10.1182/blood.2021014343. Blood. 2022. PMID: 35271698 Free PMC article.
Three decades of progress from surgery to medical therapy for isolated neuroaxis BRAF V600E-positive Langerhans cell histiocytosis management: illustrative case.
Muthiah N, Nowicki KW, Picarsic JL, D'Angelo MP, Marker DF, Andrews EG, Monaco EA 3rd, Niranjan A. Muthiah N, et al. Among authors: picarsic jl. J Neurosurg Case Lessons. 2021 May 10;1(19):CASE2118. doi: 10.3171/CASE2118. eCollection 2021 May 10. J Neurosurg Case Lessons. 2021. PMID: 35854832 Free PMC article.
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis.
Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, Boerwinkle E, Lupski JR, Plon SE, Gibbs RA, Eng CM, Yang Y, Washington GC, Porteus MH, Berquist WE, Kambham N, Singh RJ, Xia F, Enns GM, Moore DD. Gomez-Ospina N, et al. Among authors: picarsic jl. Nat Commun. 2016 Feb 18;7:10713. doi: 10.1038/ncomms10713. Nat Commun. 2016. PMID: 26888176 Free PMC article.
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